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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTCFL All Species: 4.55
Human Site: S212 Identified Species: 9.09
UniProt: Q8NI51 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NI51 NP_542185.2 663 75717 S212 T M S G D E R S D E I V L T V
Chimpanzee Pan troglodytes A2T759 682 76399 G220 E C G K T F R G N P D L I Q R
Rhesus Macaque Macaca mulatta XP_001089797 667 76197 S216 T M S G D E R S D E I V L T I
Dog Lupus familis XP_534463 582 67079 E148 V Y S L Q E V E V M K L H L L
Cat Felis silvestris
Mouse Mus musculus A2APF3 636 73090 Q184 P E E D E K D Q L P P Q G E T
Rat Rattus norvegicus Q9R1D1 737 83861 V221 Y T E E G K D V D V S V Y D F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510594 849 91989 D410 G T K L P K A D T M T P A A G
Chicken Gallus gallus Q08705 728 82810 V221 Y T E E G K D V D V S V Y D F
Frog Xenopus laevis P08045 1350 155787 Q542 E C K K G F T Q K S D L V K H
Zebra Danio Brachydanio rerio NP_001001844 798 89935 M261 N T E G D K D M D V S V Y D F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648109 818 93103 E249 P N E A E V Y E F E D N A T T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797592 939 102724 V399 I V I V R E V V E G E D G Q D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.6 93.5 66.2 N.A. 57.9 42.2 N.A. 41.9 43.1 21.1 41.3 N.A. 28.6 N.A. N.A. 27.6
Protein Similarity: 100 42.6 95.5 74.8 N.A. 70.5 55.7 N.A. 53.9 56.3 31.6 54.5 N.A. 44 N.A. N.A. 42.7
P-Site Identity: 100 6.6 93.3 13.3 N.A. 0 13.3 N.A. 0 13.3 0 26.6 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 26.6 100 26.6 N.A. 13.3 20 N.A. 6.6 20 13.3 33.3 N.A. 20 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 9 0 0 0 0 0 17 9 0 % A
% Cys: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 25 0 34 9 42 0 25 9 0 25 9 % D
% Glu: 17 9 42 17 17 34 0 17 9 25 9 0 0 9 0 % E
% Phe: 0 0 0 0 0 17 0 0 9 0 0 0 0 0 25 % F
% Gly: 9 0 9 25 25 0 0 9 0 9 0 0 17 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % H
% Ile: 9 0 9 0 0 0 0 0 0 0 17 0 9 0 9 % I
% Lys: 0 0 17 17 0 42 0 0 9 0 9 0 0 9 0 % K
% Leu: 0 0 0 17 0 0 0 0 9 0 0 25 17 9 9 % L
% Met: 0 17 0 0 0 0 0 9 0 17 0 0 0 0 0 % M
% Asn: 9 9 0 0 0 0 0 0 9 0 0 9 0 0 0 % N
% Pro: 17 0 0 0 9 0 0 0 0 17 9 9 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 17 0 0 0 9 0 17 0 % Q
% Arg: 0 0 0 0 9 0 25 0 0 0 0 0 0 0 9 % R
% Ser: 0 0 25 0 0 0 0 17 0 9 25 0 0 0 0 % S
% Thr: 17 34 0 0 9 0 9 0 9 0 9 0 0 25 17 % T
% Val: 9 9 0 9 0 9 17 25 9 25 0 42 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 17 9 0 0 0 0 9 0 0 0 0 0 25 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _