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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTCFL All Species: 1.52
Human Site: S222 Identified Species: 3.03
UniProt: Q8NI51 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NI51 NP_542185.2 663 75717 S222 I V L T V S N S N V E E Q E D
Chimpanzee Pan troglodytes A2T759 682 76399 V230 D L I Q R Q I V H T G E A S F
Rhesus Macaque Macaca mulatta XP_001089797 667 76197 L226 I V L T I S N L N V E E Q E D
Dog Lupus familis XP_534463 582 67079 S158 K L H L L E G S V A V A S E E
Cat Felis silvestris
Mouse Mus musculus A2APF3 636 73090 R194 P Q G E T D K R E E R L L L L
Rat Rattus norvegicus Q9R1D1 737 83861 E231 S V Y D F E E E Q Q E G L L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510594 849 91989 A420 T P A A G P R A T A V D P I V
Chicken Gallus gallus Q08705 728 82810 E231 S V Y D F E E E Q Q E G L L S
Frog Xenopus laevis P08045 1350 155787 V552 D L V K H I R V H T G E K P F
Zebra Danio Brachydanio rerio NP_001001844 798 89935 E271 S V Y D F E E E Q Q E G L L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648109 818 93103 E259 D N A T T E D E N A D K K D V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797592 939 102724 V409 E D G Q D P S V Y D F Y A G E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.6 93.5 66.2 N.A. 57.9 42.2 N.A. 41.9 43.1 21.1 41.3 N.A. 28.6 N.A. N.A. 27.6
Protein Similarity: 100 42.6 95.5 74.8 N.A. 70.5 55.7 N.A. 53.9 56.3 31.6 54.5 N.A. 44 N.A. N.A. 42.7
P-Site Identity: 100 6.6 86.6 13.3 N.A. 0 13.3 N.A. 0 13.3 6.6 13.3 N.A. 13.3 N.A. N.A. 0
P-Site Similarity: 100 26.6 93.3 33.3 N.A. 0 13.3 N.A. 13.3 13.3 33.3 13.3 N.A. 46.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 9 0 0 0 9 0 25 0 9 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 25 9 0 25 9 9 9 0 0 9 9 9 0 9 17 % D
% Glu: 9 0 0 9 0 42 25 34 9 9 42 34 0 25 17 % E
% Phe: 0 0 0 0 25 0 0 0 0 0 9 0 0 0 17 % F
% Gly: 0 0 17 0 9 0 9 0 0 0 17 25 0 9 0 % G
% His: 0 0 9 0 9 0 0 0 17 0 0 0 0 0 0 % H
% Ile: 17 0 9 0 9 9 9 0 0 0 0 0 0 9 0 % I
% Lys: 9 0 0 9 0 0 9 0 0 0 0 9 17 0 0 % K
% Leu: 0 25 17 9 9 0 0 9 0 0 0 9 34 34 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 17 0 25 0 0 0 0 0 0 % N
% Pro: 9 9 0 0 0 17 0 0 0 0 0 0 9 9 0 % P
% Gln: 0 9 0 17 0 9 0 0 25 25 0 0 17 0 0 % Q
% Arg: 0 0 0 0 9 0 17 9 0 0 9 0 0 0 0 % R
% Ser: 25 0 0 0 0 17 9 17 0 0 0 0 9 9 25 % S
% Thr: 9 0 0 25 17 0 0 0 9 17 0 0 0 0 0 % T
% Val: 0 42 9 0 9 0 0 25 9 17 17 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 25 0 0 0 0 0 9 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _