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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTCFL All Species: 4.24
Human Site: S243 Identified Species: 8.48
UniProt: Q8NI51 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NI51 NP_542185.2 663 75717 S243 A D A E K A K S T K N Q R K T
Chimpanzee Pan troglodytes A2T759 682 76399 V251 K T F S Q N S V L K N R H R S
Rhesus Macaque Macaca mulatta XP_001089797 667 76197 S247 A D V E K A K S T K N Q R K T
Dog Lupus familis XP_534463 582 67079 V179 P A E S T G L V K L E K G Q E
Cat Felis silvestris
Mouse Mus musculus A2APF3 636 73090 L215 G K D D E I V L T I S H L S L
Rat Rattus norvegicus Q9R1D1 737 83861 P252 V V G N M K P P K P T K I K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510594 849 91989 P441 P S P S S P A P G M R R R G T
Chicken Gallus gallus Q08705 728 82810 P252 V V G N M K P P K P T K I K K
Frog Xenopus laevis P08045 1350 155787 D573 K S F S Q N S D L H K H W R I
Zebra Danio Brachydanio rerio NP_001001844 798 89935 P292 V V G N M K P P K P T K I K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648109 818 93103 A280 K E V K L K T A S S T S Q N S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797592 939 102724 G430 A G G D E K S G I E V G G A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.6 93.5 66.2 N.A. 57.9 42.2 N.A. 41.9 43.1 21.1 41.3 N.A. 28.6 N.A. N.A. 27.6
Protein Similarity: 100 42.6 95.5 74.8 N.A. 70.5 55.7 N.A. 53.9 56.3 31.6 54.5 N.A. 44 N.A. N.A. 42.7
P-Site Identity: 100 13.3 93.3 0 N.A. 6.6 6.6 N.A. 13.3 6.6 0 6.6 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 40 93.3 13.3 N.A. 26.6 13.3 N.A. 20 13.3 13.3 13.3 N.A. 40 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 9 9 0 0 17 9 9 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 9 17 0 0 0 9 0 0 0 0 0 0 0 % D
% Glu: 0 9 9 17 17 0 0 0 0 9 9 0 0 0 9 % E
% Phe: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 9 34 0 0 9 0 9 9 0 0 9 17 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 17 9 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 9 9 0 0 25 0 9 % I
% Lys: 25 9 0 9 17 42 17 0 34 25 9 34 0 42 34 % K
% Leu: 0 0 0 0 9 0 9 9 17 9 0 0 9 0 9 % L
% Met: 0 0 0 0 25 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 25 0 17 0 0 0 0 25 0 0 9 0 % N
% Pro: 17 0 9 0 0 9 25 34 0 25 0 0 0 0 0 % P
% Gln: 0 0 0 0 17 0 0 0 0 0 0 17 9 9 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 9 17 25 17 0 % R
% Ser: 0 17 0 34 9 0 25 17 9 9 9 9 0 9 17 % S
% Thr: 0 9 0 0 9 0 9 0 25 0 34 0 0 0 25 % T
% Val: 25 25 17 0 0 0 9 17 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _