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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTCFL All Species: 30.3
Human Site: S355 Identified Species: 60.61
UniProt: Q8NI51 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NI51 NP_542185.2 663 75717 S355 K Y A S V E A S K L K R H V R
Chimpanzee Pan troglodytes A2T759 682 76399 N363 K A F R R S S N L I K H H R T
Rhesus Macaque Macaca mulatta XP_001089797 667 76197 S359 K Y A S V E A S K L K R H V R
Dog Lupus familis XP_534463 582 67079 C291 T A E K P H M C H L C L K A F
Cat Felis silvestris
Mouse Mus musculus A2APF3 636 73090 E327 M A F V T S G E L V R H R R Y
Rat Rattus norvegicus Q9R1D1 737 83861 S364 D Y A S V E V S K L K R H I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510594 849 91989 S553 K Y A S V E A S K L K R H I R
Chicken Gallus gallus Q08705 728 82810 S364 D Y A S V E V S K L K R H I R
Frog Xenopus laevis P08045 1350 155787 S685 K R F T E G S S L V K H R R T
Zebra Danio Brachydanio rerio NP_001001844 798 89935 S404 D Y A S V E V S K L K R H I R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648109 818 93103 T392 T Y A S V E L T K L R R H M T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797592 939 102724 S542 D Y L S V E A S K I K R H M R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.6 93.5 66.2 N.A. 57.9 42.2 N.A. 41.9 43.1 21.1 41.3 N.A. 28.6 N.A. N.A. 27.6
Protein Similarity: 100 42.6 95.5 74.8 N.A. 70.5 55.7 N.A. 53.9 56.3 31.6 54.5 N.A. 44 N.A. N.A. 42.7
P-Site Identity: 100 20 100 6.6 N.A. 0 80 N.A. 93.3 80 20 80 N.A. 60 N.A. N.A. 73.3
P-Site Similarity: 100 40 100 6.6 N.A. 13.3 86.6 N.A. 100 86.6 40 86.6 N.A. 80 N.A. N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 59 0 0 0 34 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % C
% Asp: 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 9 0 9 67 0 9 0 0 0 0 0 0 0 % E
% Phe: 0 0 25 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 9 0 0 9 0 0 25 75 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 17 0 0 0 34 0 % I
% Lys: 42 0 0 9 0 0 0 0 67 0 75 0 9 0 0 % K
% Leu: 0 0 9 0 0 0 9 0 25 67 0 9 0 0 0 % L
% Met: 9 0 0 0 0 0 9 0 0 0 0 0 0 17 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 9 9 0 0 0 0 0 17 67 17 25 59 % R
% Ser: 0 0 0 67 0 17 17 67 0 0 0 0 0 0 0 % S
% Thr: 17 0 0 9 9 0 0 9 0 0 0 0 0 0 25 % T
% Val: 0 0 0 9 67 0 25 0 0 17 0 0 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _