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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTCFL All Species: 5.76
Human Site: S575 Identified Species: 11.52
UniProt: Q8NI51 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NI51 NP_542185.2 663 75717 S575 C G S G E A K S A A S G K G R
Chimpanzee Pan troglodytes A2T759 682 76399 E605 E K P Y T C V E C G K G F S Q
Rhesus Macaque Macaca mulatta XP_001089797 667 76197 S579 C G S G E A K S A A S G K G K
Dog Lupus familis XP_534463 582 67079 V507 K Q E R H M T V H I R T H T G
Cat Felis silvestris
Mouse Mus musculus A2APF3 636 73090 L547 N F V P N L H L C L K C D K R
Rat Rattus norvegicus Q9R1D1 737 83861 E584 C A G P D G V E G E N G G E T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510594 849 91989 A773 C E P D K S K A V T S R N G R
Chicken Gallus gallus Q08705 728 82810 E584 C S G L D G G E G E N G G E T
Frog Xenopus laevis P08045 1350 155787 P1193 H T G E K P Y P C S T C G K S
Zebra Danio Brachydanio rerio NP_001001844 798 89935 D624 C T G M D S A D G E N G T P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648109 818 93103 R616 H D D S A N A R E K R R R L K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797592 939 102724 T761 Q I Q E E E E T E E M V E P H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.6 93.5 66.2 N.A. 57.9 42.2 N.A. 41.9 43.1 21.1 41.3 N.A. 28.6 N.A. N.A. 27.6
Protein Similarity: 100 42.6 95.5 74.8 N.A. 70.5 55.7 N.A. 53.9 56.3 31.6 54.5 N.A. 44 N.A. N.A. 42.7
P-Site Identity: 100 6.6 93.3 0 N.A. 6.6 13.3 N.A. 33.3 13.3 0 13.3 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 13.3 100 0 N.A. 6.6 26.6 N.A. 53.3 26.6 20 33.3 N.A. 13.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 17 17 9 17 17 0 0 0 0 0 % A
% Cys: 50 0 0 0 0 9 0 0 25 0 0 17 0 0 0 % C
% Asp: 0 9 9 9 25 0 0 9 0 0 0 0 9 0 0 % D
% Glu: 9 9 9 17 25 9 9 25 17 34 0 0 9 17 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 17 34 17 0 17 9 0 25 9 0 50 25 25 9 % G
% His: 17 0 0 0 9 0 9 0 9 0 0 0 9 0 9 % H
% Ile: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 9 9 0 0 17 0 25 0 0 9 17 0 17 17 17 % K
% Leu: 0 0 0 9 0 9 0 9 0 9 0 0 0 9 0 % L
% Met: 0 0 0 9 0 9 0 0 0 0 9 0 0 0 0 % M
% Asn: 9 0 0 0 9 9 0 0 0 0 25 0 9 0 0 % N
% Pro: 0 0 17 17 0 9 0 9 0 0 0 0 0 17 9 % P
% Gln: 9 9 9 0 0 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 0 0 0 9 0 0 0 9 0 0 17 17 9 0 25 % R
% Ser: 0 9 17 9 0 17 0 17 0 9 25 0 0 9 9 % S
% Thr: 0 17 0 0 9 0 9 9 0 9 9 9 9 9 17 % T
% Val: 0 0 9 0 0 0 17 9 9 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _