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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTCFL All Species: 5.76
Human Site: T218 Identified Species: 11.52
UniProt: Q8NI51 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NI51 NP_542185.2 663 75717 T218 R S D E I V L T V S N S N V E
Chimpanzee Pan troglodytes A2T759 682 76399 Q226 R G N P D L I Q R Q I V H T G
Rhesus Macaque Macaca mulatta XP_001089797 667 76197 T222 R S D E I V L T I S N L N V E
Dog Lupus familis XP_534463 582 67079 L154 V E V M K L H L L E G S V A V
Cat Felis silvestris
Mouse Mus musculus A2APF3 636 73090 E190 D Q L P P Q G E T D K R E E R
Rat Rattus norvegicus Q9R1D1 737 83861 D227 D V D V S V Y D F E E E Q Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510594 849 91989 A416 A D T M T P A A G P R A T A V
Chicken Gallus gallus Q08705 728 82810 D227 D V D V S V Y D F E E E Q Q E
Frog Xenopus laevis P08045 1350 155787 K548 T Q K S D L V K H I R V H T G
Zebra Danio Brachydanio rerio NP_001001844 798 89935 D267 D M D V S V Y D F E E E Q Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648109 818 93103 T255 Y E F E D N A T T E D E N A D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797592 939 102724 Q405 V V E G E D G Q D P S V Y D F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.6 93.5 66.2 N.A. 57.9 42.2 N.A. 41.9 43.1 21.1 41.3 N.A. 28.6 N.A. N.A. 27.6
Protein Similarity: 100 42.6 95.5 74.8 N.A. 70.5 55.7 N.A. 53.9 56.3 31.6 54.5 N.A. 44 N.A. N.A. 42.7
P-Site Identity: 100 6.6 86.6 6.6 N.A. 0 20 N.A. 0 20 0 20 N.A. 20 N.A. N.A. 0
P-Site Similarity: 100 33.3 93.3 20 N.A. 0 20 N.A. 6.6 20 20 20 N.A. 33.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 17 9 0 0 0 9 0 25 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 34 9 42 0 25 9 0 25 9 9 9 0 0 9 9 % D
% Glu: 0 17 9 25 9 0 0 9 0 42 25 34 9 9 42 % E
% Phe: 0 0 9 0 0 0 0 0 25 0 0 0 0 0 9 % F
% Gly: 0 9 0 9 0 0 17 0 9 0 9 0 0 0 17 % G
% His: 0 0 0 0 0 0 9 0 9 0 0 0 17 0 0 % H
% Ile: 0 0 0 0 17 0 9 0 9 9 9 0 0 0 0 % I
% Lys: 0 0 9 0 9 0 0 9 0 0 9 0 0 0 0 % K
% Leu: 0 0 9 0 0 25 17 9 9 0 0 9 0 0 0 % L
% Met: 0 9 0 17 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 9 0 0 0 0 17 0 25 0 0 % N
% Pro: 0 0 0 17 9 9 0 0 0 17 0 0 0 0 0 % P
% Gln: 0 17 0 0 0 9 0 17 0 9 0 0 25 25 0 % Q
% Arg: 25 0 0 0 0 0 0 0 9 0 17 9 0 0 9 % R
% Ser: 0 17 0 9 25 0 0 0 0 17 9 17 0 0 0 % S
% Thr: 9 0 9 0 9 0 0 25 17 0 0 0 9 17 0 % T
% Val: 17 25 9 25 0 42 9 0 9 0 0 25 9 17 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 25 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _