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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTCFL All Species: 28.48
Human Site: T298 Identified Species: 56.97
UniProt: Q8NI51 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NI51 NP_542185.2 663 75717 T298 L K T F R T V T L L R N H V N
Chimpanzee Pan troglodytes A2T759 682 76399 S306 G K A F S Q N S S L K K H Q K
Rhesus Macaque Macaca mulatta XP_001089797 667 76197 T302 L K T F R T V T L L R N H V N
Dog Lupus familis XP_534463 582 67079 K234 N V E E E E E K P A S G Q G H
Cat Felis silvestris
Mouse Mus musculus A2APF3 636 73090 S270 P F T S S K L S T F N R H I K
Rat Rattus norvegicus Q9R1D1 737 83861 T307 G R A F R T V T L L R N H L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510594 849 91989 T496 L K A F R S A T L L R N H V N
Chicken Gallus gallus Q08705 728 82810 T307 G R A F R T V T L L R N H L N
Frog Xenopus laevis P08045 1350 155787 S628 Q K G F I Q K S A L T K H S R
Zebra Danio Brachydanio rerio NP_001001844 798 89935 T347 G R A F R T V T L L R N H L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648109 818 93103 V335 E R S F R S N V G L Q N H I N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797592 939 102724 T485 G R I F R T S T L L R N H E N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.6 93.5 66.2 N.A. 57.9 42.2 N.A. 41.9 43.1 21.1 41.3 N.A. 28.6 N.A. N.A. 27.6
Protein Similarity: 100 42.6 95.5 74.8 N.A. 70.5 55.7 N.A. 53.9 56.3 31.6 54.5 N.A. 44 N.A. N.A. 42.7
P-Site Identity: 100 26.6 100 0 N.A. 13.3 73.3 N.A. 80 73.3 26.6 73.3 N.A. 40 N.A. N.A. 66.6
P-Site Similarity: 100 40 100 6.6 N.A. 33.3 86.6 N.A. 86.6 86.6 33.3 86.6 N.A. 73.3 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 42 0 0 0 9 0 9 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 9 9 9 9 9 0 0 0 0 0 0 9 0 % E
% Phe: 0 9 0 84 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 42 0 9 0 0 0 0 0 9 0 0 9 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 92 0 9 % H
% Ile: 0 0 9 0 9 0 0 0 0 0 0 0 0 17 0 % I
% Lys: 0 42 0 0 0 9 9 9 0 0 9 17 0 0 17 % K
% Leu: 25 0 0 0 0 0 9 0 59 84 0 0 0 25 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 17 0 0 0 9 67 0 0 67 % N
% Pro: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % P
% Gln: 9 0 0 0 0 17 0 0 0 0 9 0 9 9 0 % Q
% Arg: 0 42 0 0 67 0 0 0 0 0 59 9 0 0 9 % R
% Ser: 0 0 9 9 17 17 9 25 9 0 9 0 0 9 0 % S
% Thr: 0 0 25 0 0 50 0 59 9 0 9 0 0 0 0 % T
% Val: 0 9 0 0 0 0 42 9 0 0 0 0 0 25 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _