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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTCFL All Species: 35.76
Human Site: T306 Identified Species: 71.52
UniProt: Q8NI51 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NI51 NP_542185.2 663 75717 T306 L L R N H V N T H T G T R P Y
Chimpanzee Pan troglodytes A2T759 682 76399 S314 S L K K H Q K S H M S E K P Y
Rhesus Macaque Macaca mulatta XP_001089797 667 76197 T310 L L R N H V N T H T G T R P Y
Dog Lupus familis XP_534463 582 67079 V242 P A S G Q G H V E K A N S T K
Cat Felis silvestris
Mouse Mus musculus A2APF3 636 73090 I278 T F N R H I K I H S N E R P H
Rat Rattus norvegicus Q9R1D1 737 83861 T315 L L R N H L N T H T G T R P H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510594 849 91989 T504 L L R N H V N T H T G T K P Y
Chicken Gallus gallus Q08705 728 82810 T315 L L R N H L N T H T G T R P H
Frog Xenopus laevis P08045 1350 155787 T636 A L T K H S R T H T G E K P Y
Zebra Danio Brachydanio rerio NP_001001844 798 89935 T355 L L R N H L N T H T G T R P H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648109 818 93103 T343 G L Q N H I N T H M G N K P H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797592 939 102724 T493 L L R N H E N T H S G T K P Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.6 93.5 66.2 N.A. 57.9 42.2 N.A. 41.9 43.1 21.1 41.3 N.A. 28.6 N.A. N.A. 27.6
Protein Similarity: 100 42.6 95.5 74.8 N.A. 70.5 55.7 N.A. 53.9 56.3 31.6 54.5 N.A. 44 N.A. N.A. 42.7
P-Site Identity: 100 33.3 100 0 N.A. 26.6 86.6 N.A. 93.3 86.6 53.3 86.6 N.A. 53.3 N.A. N.A. 80
P-Site Similarity: 100 53.3 100 6.6 N.A. 46.6 100 N.A. 100 100 60 100 N.A. 80 N.A. N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 9 0 0 9 0 0 25 0 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 9 0 9 0 0 0 0 75 0 0 0 0 % G
% His: 0 0 0 0 92 0 9 0 92 0 0 0 0 0 42 % H
% Ile: 0 0 0 0 0 17 0 9 0 0 0 0 0 0 0 % I
% Lys: 0 0 9 17 0 0 17 0 0 9 0 0 42 0 9 % K
% Leu: 59 84 0 0 0 25 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % M
% Asn: 0 0 9 67 0 0 67 0 0 0 9 17 0 0 0 % N
% Pro: 9 0 0 0 0 0 0 0 0 0 0 0 0 92 0 % P
% Gln: 0 0 9 0 9 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 59 9 0 0 9 0 0 0 0 0 50 0 0 % R
% Ser: 9 0 9 0 0 9 0 9 0 17 9 0 9 0 0 % S
% Thr: 9 0 9 0 0 0 0 75 0 59 0 59 0 9 0 % T
% Val: 0 0 0 0 0 25 0 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _