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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTCFL All Species: 5.45
Human Site: T52 Identified Species: 10.91
UniProt: Q8NI51 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NI51 NP_542185.2 663 75717 T52 S E L E A E R T S G A F Q D S
Chimpanzee Pan troglodytes A2T759 682 76399 I58 S D T E L E A I C P H Y Q Q P
Rhesus Macaque Macaca mulatta XP_001089797 667 76197 T52 R E L E A A C T S G A L Q D S
Dog Lupus familis XP_534463 582 67079 E11 T E I S V L P E Q F T Q I K E
Cat Felis silvestris
Mouse Mus musculus A2APF3 636 73090 E42 V Q R V E A Q E G V V K E V E
Rat Rattus norvegicus Q9R1D1 737 83861 G48 P Q N Q T D G G E V V Q D V N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510594 849 91989 V240 Q P R L R R C V A I S I Q D E
Chicken Gallus gallus Q08705 728 82810 V50 N Q A D G G E V V Q D V N S G
Frog Xenopus laevis P08045 1350 155787 C74 S D W A A E N C K R A Q M H K
Zebra Danio Brachydanio rerio NP_001001844 798 89935 M92 L Q M K T E V M E A A V G A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648109 818 93103 N51 E A I D L D E N G A E A G G S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797592 939 102724 T174 T F M Q Q L D T S N L V D E N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.6 93.5 66.2 N.A. 57.9 42.2 N.A. 41.9 43.1 21.1 41.3 N.A. 28.6 N.A. N.A. 27.6
Protein Similarity: 100 42.6 95.5 74.8 N.A. 70.5 55.7 N.A. 53.9 56.3 31.6 54.5 N.A. 44 N.A. N.A. 42.7
P-Site Identity: 100 26.6 73.3 6.6 N.A. 0 0 N.A. 13.3 0 26.6 13.3 N.A. 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 40 73.3 20 N.A. 20 26.6 N.A. 26.6 20 33.3 33.3 N.A. 26.6 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 9 25 17 9 0 9 17 34 9 0 9 0 % A
% Cys: 0 0 0 0 0 0 17 9 9 0 0 0 0 0 0 % C
% Asp: 0 17 0 17 0 17 9 0 0 0 9 0 17 25 0 % D
% Glu: 9 25 0 25 9 34 17 17 17 0 9 0 9 9 25 % E
% Phe: 0 9 0 0 0 0 0 0 0 9 0 9 0 0 0 % F
% Gly: 0 0 0 0 9 9 9 9 17 17 0 0 17 9 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 9 0 % H
% Ile: 0 0 17 0 0 0 0 9 0 9 0 9 9 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 9 0 0 9 0 9 9 % K
% Leu: 9 0 17 9 17 17 0 0 0 0 9 9 0 0 0 % L
% Met: 0 0 17 0 0 0 0 9 0 0 0 0 9 0 0 % M
% Asn: 9 0 9 0 0 0 9 9 0 9 0 0 9 0 17 % N
% Pro: 9 9 0 0 0 0 9 0 0 9 0 0 0 0 17 % P
% Gln: 9 34 0 17 9 0 9 0 9 9 0 25 34 9 0 % Q
% Arg: 9 0 17 0 9 9 9 0 0 9 0 0 0 0 0 % R
% Ser: 25 0 0 9 0 0 0 0 25 0 9 0 0 9 25 % S
% Thr: 17 0 9 0 17 0 0 25 0 0 9 0 0 0 0 % T
% Val: 9 0 0 9 9 0 9 17 9 17 17 25 0 17 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _