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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTCFL All Species: 7.88
Human Site: T544 Identified Species: 15.76
UniProt: Q8NI51 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NI51 NP_542185.2 663 75717 T544 H D A N F I P T V Y K C S K C
Chimpanzee Pan troglodytes A2T759 682 76399 E574 H N G L K P H E C N Q C G K A
Rhesus Macaque Macaca mulatta XP_001089797 667 76197 T548 H D A N F I P T V Y K C C K C
Dog Lupus familis XP_534463 582 67079 A476 S V F H E R Y A L I Q H Q K T
Cat Felis silvestris
Mouse Mus musculus A2APF3 636 73090 C516 T G E K P F S C L A C N K H F
Rat Rattus norvegicus Q9R1D1 737 83861 A553 H D P N F V P A A F V C S K C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510594 849 91989 I742 H D E N F T P I V Y E C P K C
Chicken Gallus gallus Q08705 728 82810 A553 H D P N F V P A A F V C S K C
Frog Xenopus laevis P08045 1350 155787 Q1162 W R M H T G E Q P Y T C K E C
Zebra Danio Brachydanio rerio NP_001001844 798 89935 T593 H D P N F V P T S F V C T K C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648109 818 93103 K585 Q P P E P R E K L H K C P S C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797592 939 102724 G730 N L I Q E A D G T K K R K A T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.6 93.5 66.2 N.A. 57.9 42.2 N.A. 41.9 43.1 21.1 41.3 N.A. 28.6 N.A. N.A. 27.6
Protein Similarity: 100 42.6 95.5 74.8 N.A. 70.5 55.7 N.A. 53.9 56.3 31.6 54.5 N.A. 44 N.A. N.A. 42.7
P-Site Identity: 100 20 93.3 6.6 N.A. 0 60 N.A. 66.6 60 20 60 N.A. 20 N.A. N.A. 6.6
P-Site Similarity: 100 33.3 93.3 26.6 N.A. 6.6 73.3 N.A. 73.3 73.3 33.3 80 N.A. 33.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 0 9 0 25 17 9 0 0 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 9 9 0 9 75 9 0 67 % C
% Asp: 0 50 0 0 0 0 9 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 17 9 17 0 17 9 0 0 9 0 0 9 0 % E
% Phe: 0 0 9 0 50 9 0 0 0 25 0 0 0 0 9 % F
% Gly: 0 9 9 0 0 9 0 9 0 0 0 0 9 0 0 % G
% His: 59 0 0 17 0 0 9 0 0 9 0 9 0 9 0 % H
% Ile: 0 0 9 0 0 17 0 9 0 9 0 0 0 0 0 % I
% Lys: 0 0 0 9 9 0 0 9 0 9 34 0 25 67 0 % K
% Leu: 0 9 0 9 0 0 0 0 25 0 0 0 0 0 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 9 0 50 0 0 0 0 0 9 0 9 0 0 0 % N
% Pro: 0 9 34 0 17 9 50 0 9 0 0 0 17 0 0 % P
% Gln: 9 0 0 9 0 0 0 9 0 0 17 0 9 0 0 % Q
% Arg: 0 9 0 0 0 17 0 0 0 0 0 9 0 0 0 % R
% Ser: 9 0 0 0 0 0 9 0 9 0 0 0 25 9 0 % S
% Thr: 9 0 0 0 9 9 0 25 9 0 9 0 9 0 17 % T
% Val: 0 9 0 0 0 25 0 0 25 0 25 0 0 0 0 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 34 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _