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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CTCFL All Species: 7.88
Human Site: T641 Identified Species: 15.76
UniProt: Q8NI51 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NI51 NP_542185.2 663 75717 T641 P V A C R E T T A R V K E E V
Chimpanzee Pan troglodytes A2T759 682 76399 A661 V K P Y D C A A C G K A F S Q
Rhesus Macaque Macaca mulatta XP_001089797 667 76197 T645 P G A C G E T T A R V K E D V
Dog Lupus familis XP_534463 582 67079 R561 K C G K G F S R W V S L L K S
Cat Felis silvestris
Mouse Mus musculus A2APF3 636 73090 E614 Q A L G H Q G E A A G S Q S P
Rat Rattus norvegicus Q9R1D1 737 83861 Q715 E G E E E E A Q A A P A D A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510594 849 91989 I827 V P V L S G E I S S V V E K V
Chicken Gallus gallus Q08705 728 82810 Q706 V E E E E E A Q P A V V E A P
Frog Xenopus laevis P08045 1350 155787 L1328 W K G D Y A Q L L Q I P C G L
Zebra Danio Brachydanio rerio NP_001001844 798 89935 L776 A D V E T V Q L T V P E A A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648109 818 93103 S777 P S A N S K I S A K N C F G F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797592 939 102724 S890 E V S A P R E S S S I T Q E Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.6 93.5 66.2 N.A. 57.9 42.2 N.A. 41.9 43.1 21.1 41.3 N.A. 28.6 N.A. N.A. 27.6
Protein Similarity: 100 42.6 95.5 74.8 N.A. 70.5 55.7 N.A. 53.9 56.3 31.6 54.5 N.A. 44 N.A. N.A. 42.7
P-Site Identity: 100 0 80 0 N.A. 6.6 13.3 N.A. 20 20 0 0 N.A. 20 N.A. N.A. 13.3
P-Site Similarity: 100 0 86.6 13.3 N.A. 20 20 N.A. 33.3 20 20 6.6 N.A. 40 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 25 9 0 9 25 9 42 25 0 17 9 25 0 % A
% Cys: 0 9 0 17 0 9 0 0 9 0 0 9 9 0 0 % C
% Asp: 0 9 0 9 9 0 0 0 0 0 0 0 9 9 0 % D
% Glu: 17 9 17 25 17 34 17 9 0 0 0 9 34 17 0 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 0 0 17 0 9 % F
% Gly: 0 17 17 9 17 9 9 0 0 9 9 0 0 17 0 % G
% His: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 9 0 0 17 0 0 0 0 % I
% Lys: 9 17 0 9 0 9 0 0 0 9 9 17 0 17 0 % K
% Leu: 0 0 9 9 0 0 0 17 9 0 0 9 9 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % N
% Pro: 25 9 9 0 9 0 0 0 9 0 17 9 0 0 34 % P
% Gln: 9 0 0 0 0 9 17 17 0 9 0 0 17 0 17 % Q
% Arg: 0 0 0 0 9 9 0 9 0 17 0 0 0 0 0 % R
% Ser: 0 9 9 0 17 0 9 17 17 17 9 9 0 17 9 % S
% Thr: 0 0 0 0 9 0 17 17 9 0 0 9 0 0 0 % T
% Val: 25 17 17 0 0 9 0 0 0 17 34 17 0 0 25 % V
% Trp: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _