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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18A
All Species:
12.73
Human Site:
S778
Identified Species:
25.45
UniProt:
Q8NI77
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI77
NP_112494.3
898
102281
S778
T
I
C
E
D
I
K
S
S
K
C
K
L
P
E
Chimpanzee
Pan troglodytes
XP_001138074
898
102191
S778
T
I
C
E
D
I
K
S
S
K
C
K
L
P
E
Rhesus Macaque
Macaca mulatta
XP_001089262
897
102178
S777
T
I
C
E
D
I
K
S
L
K
C
K
L
P
K
Dog
Lupus familis
XP_542544
899
102337
K779
F
I
I
C
E
D
I
K
N
L
K
S
K
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD7
886
100916
R766
S
T
L
C
D
S
I
R
G
L
K
N
K
W
P
Rat
Rattus norvegicus
Q4KLL9
826
91176
L707
L
Q
N
C
S
T
P
L
T
L
P
T
R
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511000
709
81248
G590
F
L
A
L
K
E
A
G
L
A
T
T
A
I
E
Chicken
Gallus gallus
Q5ZLK6
797
86563
C678
N
C
C
T
P
T
V
C
D
L
N
V
T
Y
S
Frog
Xenopus laevis
Q7ZXX2
997
114958
K865
N
L
W
H
R
T
Q
K
K
Q
A
Q
K
L
E
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
S766
S
P
E
D
P
G
R
S
T
L
Q
A
L
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001119963
717
81330
T598
M
I
K
M
M
S
T
T
L
Q
N
Y
Y
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P46872
699
78679
S580
L
E
N
V
R
E
L
S
R
E
L
R
L
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
85.8
N.A.
75.8
35.5
N.A.
57.4
37.8
28.9
46.2
N.A.
N.A.
34.8
N.A.
27.8
Protein Similarity:
100
99.8
98.3
91.8
N.A.
84.9
52.2
N.A.
67.4
53.2
50.2
62.6
N.A.
N.A.
50
N.A.
45.6
P-Site Identity:
100
100
86.6
6.6
N.A.
6.6
0
N.A.
6.6
6.6
6.6
13.3
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
93.3
20
N.A.
13.3
6.6
N.A.
13.3
6.6
33.3
40
N.A.
N.A.
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
9
0
0
9
9
9
9
0
9
% A
% Cys:
0
9
34
25
0
0
0
9
0
0
25
0
0
0
0
% C
% Asp:
0
0
0
9
34
9
0
0
9
0
0
0
0
17
0
% D
% Glu:
0
9
9
25
9
17
0
0
0
9
0
0
0
0
34
% E
% Phe:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
9
9
0
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
42
9
0
0
25
17
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
9
0
9
0
25
17
9
25
17
25
25
0
9
% K
% Leu:
17
17
9
9
0
0
9
9
25
42
9
0
42
9
17
% L
% Met:
9
0
0
9
9
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
17
0
17
0
0
0
0
0
9
0
17
9
0
0
0
% N
% Pro:
0
9
0
0
17
0
9
0
0
0
9
0
0
25
17
% P
% Gln:
0
9
0
0
0
0
9
0
0
17
9
9
0
0
0
% Q
% Arg:
0
0
0
0
17
0
9
9
9
0
0
9
9
9
0
% R
% Ser:
17
0
0
0
9
17
0
42
17
0
0
9
0
17
9
% S
% Thr:
25
9
0
9
0
25
9
9
17
0
9
17
9
0
0
% T
% Val:
0
0
0
9
0
0
9
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
9
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _