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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRPEL2
All Species:
16.67
Human Site:
S128
Identified Species:
26.19
UniProt:
Q8TAA5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TAA5
NP_689620.2
225
25431
S128
E
K
T
T
E
C
I
S
E
E
S
E
P
E
D
Chimpanzee
Pan troglodytes
XP_001163063
225
25422
S128
E
K
T
T
E
C
I
S
E
E
S
E
P
E
D
Rhesus Macaque
Macaca mulatta
XP_001105579
225
25347
S128
E
K
T
T
E
C
I
S
E
E
S
E
P
E
N
Dog
Lupus familis
XP_546313
281
31029
S184
E
K
T
T
E
Y
I
S
E
E
T
E
P
G
D
Cat
Felis silvestris
Mouse
Mus musculus
O88396
224
25011
S127
E
K
T
A
K
C
C
S
E
G
A
E
P
E
D
Rat
Rattus norvegicus
P97576
217
24279
P126
E
K
A
T
Q
S
V
P
K
E
E
V
S
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508203
195
21398
G107
I
S
R
D
A
A
P
G
D
Q
K
P
T
L
E
Chicken
Gallus gallus
XP_001231561
222
24655
A128
E
K
T
A
E
S
A
A
E
E
A
E
P
T
N
Frog
Xenopus laevis
NP_001088483
216
23876
V116
Q
S
F
C
R
D
L
V
E
V
A
D
I
I
E
Zebra Danio
Brachydanio rerio
XP_001344119
217
24474
V116
Q
S
F
C
R
D
L
V
E
V
A
D
L
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48604
213
23908
P124
G
H
A
T
Q
A
V
P
K
D
K
L
S
G
N
Honey Bee
Apis mellifera
XP_624159
232
26421
P142
G
K
A
T
E
S
V
P
K
N
E
L
T
E
K
Nematode Worm
Caenorhab. elegans
Q18421
237
26430
K145
D
I
A
V
K
S
V
K
P
E
D
L
E
S
G
Sea Urchin
Strong. purpuratus
XP_798953
168
18775
G80
V
P
K
D
A
V
S
G
A
D
A
N
I
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9P5U4
238
26809
P142
E
R
A
L
S
V
V
P
Q
D
K
L
K
S
E
Conservation
Percent
Protein Identity:
100
99.5
96
71.1
N.A.
84.8
40.4
N.A.
61.3
61.3
47.5
51.1
N.A.
34.6
35.7
30.7
34.2
Protein Similarity:
100
99.5
98.6
74.3
N.A.
91.5
63.1
N.A.
72
78.2
68
68.8
N.A.
53.7
54.7
51.4
50.2
P-Site Identity:
100
100
93.3
80
N.A.
66.6
26.6
N.A.
0
53.3
6.6
6.6
N.A.
6.6
26.6
6.6
0
P-Site Similarity:
100
100
100
86.6
N.A.
80
53.3
N.A.
20
73.3
40
40
N.A.
40
40
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
28.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
50.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
14
14
14
7
7
7
0
34
0
0
0
0
% A
% Cys:
0
0
0
14
0
27
7
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
14
0
14
0
0
7
20
7
14
0
0
27
% D
% Glu:
54
0
0
0
40
0
0
0
54
47
14
40
7
34
27
% E
% Phe:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
14
0
0
0
0
0
0
14
0
7
0
0
0
14
7
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
7
7
0
0
0
0
27
0
0
0
0
0
14
7
0
% I
% Lys:
0
54
7
0
14
0
0
7
20
0
20
0
7
0
7
% K
% Leu:
0
0
0
7
0
0
14
0
0
0
0
27
7
14
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
0
7
0
7
27
% N
% Pro:
0
7
0
0
0
0
7
27
7
0
0
7
40
0
0
% P
% Gln:
14
0
0
0
14
0
0
0
7
7
0
0
0
0
0
% Q
% Arg:
0
7
7
0
14
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
20
0
0
7
27
7
34
0
0
20
0
14
14
0
% S
% Thr:
0
0
40
47
0
0
0
0
0
0
7
0
14
7
0
% T
% Val:
7
0
0
7
0
14
34
14
0
14
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _