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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VANGL1
All Species:
29.7
Human Site:
S446
Identified Species:
72.59
UniProt:
Q8TAA9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TAA9
NP_620409.1
524
59975
S446
A
F
L
E
R
Y
L
S
A
G
P
T
L
Q
Y
Chimpanzee
Pan troglodytes
XP_513676
524
59944
S446
A
F
L
E
R
Y
L
S
A
G
P
T
L
Q
Y
Rhesus Macaque
Macaca mulatta
XP_001115459
590
67361
A512
A
F
L
E
R
Y
L
A
A
G
P
T
I
Q
Y
Dog
Lupus familis
XP_540251
524
59825
S446
A
F
L
E
R
Y
L
S
A
G
P
T
L
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q80Z96
526
60031
S448
A
F
L
E
R
Y
L
S
A
G
P
T
L
Q
Y
Rat
Rattus norvegicus
NP_001103054
526
60086
S448
A
F
L
E
R
Y
L
S
A
G
P
T
L
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232441
524
59613
S446
A
F
L
E
R
Y
L
S
P
G
P
T
L
Q
Y
Frog
Xenopus laevis
Q90X64
521
60078
G443
A
F
L
E
R
Y
L
G
P
G
P
T
I
Q
Y
Zebra Danio
Brachydanio rerio
Q8UVJ6
526
60063
T448
A
F
L
E
R
Y
L
T
P
G
P
T
M
Q
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477177
581
65856
T503
A
F
L
E
P
Y
L
T
E
S
P
V
M
Q
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
64.4
96.5
N.A.
94.8
95
N.A.
N.A.
88.3
72.9
66.5
N.A.
43.2
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
76.6
98.6
N.A.
97.7
97.7
N.A.
N.A.
94
85.3
80.6
N.A.
62.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
100
N.A.
100
100
N.A.
N.A.
93.3
80
80
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
93.3
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
100
0
0
0
0
0
0
10
60
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
100
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
90
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
100
0
0
0
100
0
0
0
0
0
60
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
30
0
100
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% Q
% Arg:
0
0
0
0
90
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
60
0
10
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
20
0
0
0
90
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
90
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _