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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VANGL1 All Species: 36.97
Human Site: Y216 Identified Species: 90.37
UniProt: Q8TAA9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TAA9 NP_620409.1 524 59975 Y216 L D S R D R N Y Q G I V Q Y A
Chimpanzee Pan troglodytes XP_513676 524 59944 Y216 L D S R D R N Y Q G I V Q Y A
Rhesus Macaque Macaca mulatta XP_001115459 590 67361 Y281 L D A R E R S Y Q G V V Q F A
Dog Lupus familis XP_540251 524 59825 Y216 L D S R D R N Y Q G I V Q Y A
Cat Felis silvestris
Mouse Mus musculus Q80Z96 526 60031 Y218 L D S R D Q N Y K D I V Q Y A
Rat Rattus norvegicus NP_001103054 526 60086 Y218 L D S R D Q N Y K D I V Q Y A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232441 524 59613 Y216 L D S K D T N Y Q G I V Q Y A
Frog Xenopus laevis Q90X64 521 60078 Y212 L E S R D K N Y Q G I V Q Y A
Zebra Danio Brachydanio rerio Q8UVJ6 526 60063 Y213 L E P R E R D Y R G I V G Y A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477177 581 65856 Y271 T G G D A V D Y K S L V G Y A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 64.4 96.5 N.A. 94.8 95 N.A. N.A. 88.3 72.9 66.5 N.A. 43.2 N.A. N.A. N.A.
Protein Similarity: 100 99.8 76.6 98.6 N.A. 97.7 97.7 N.A. N.A. 94 85.3 80.6 N.A. 62.3 N.A. N.A. N.A.
P-Site Identity: 100 100 66.6 100 N.A. 80 80 N.A. N.A. 86.6 86.6 60 N.A. 26.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 93.3 100 86.6 N.A. 46.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 100 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 70 0 10 70 0 20 0 0 20 0 0 0 0 0 % D
% Glu: 0 20 0 0 20 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 10 10 0 0 0 0 0 0 70 0 0 20 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 80 0 0 0 0 % I
% Lys: 0 0 0 10 0 10 0 0 30 0 0 0 0 0 0 % K
% Leu: 90 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 20 0 0 60 0 0 0 80 0 0 % Q
% Arg: 0 0 0 80 0 50 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 0 70 0 0 0 10 0 0 10 0 0 0 0 0 % S
% Thr: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 10 0 0 0 0 10 100 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 90 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _