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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RFESD All Species: 24.55
Human Site: S142 Identified Species: 67.5
UniProt: Q8TAC1 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TAC1 NP_001124537.1 157 17762 S142 N E P F K C D S D F Y A T G D
Chimpanzee Pan troglodytes XP_001136313 210 23700 S195 N E P F K C D S D F Y A T G D
Rhesus Macaque Macaca mulatta XP_001093050 158 17858 S142 S E P F K C D S D F Y A T G D
Dog Lupus familis XP_546019 233 26102 S217 N E P F K C D S D F Y A T G D
Cat Felis silvestris
Mouse Mus musculus Q8K2P6 157 17948 S142 K E P F K C D S D Y Y A T G E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508796 240 26609 S218 D T S I R Y D S D Y Y A S E K
Chicken Gallus gallus XP_424710 187 21234 S170 D L S V S F D S D Y F A E K Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_688339 160 17836 S139 D C A G A V D S D I Y Q T E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789096 161 18396 I137 S V T F P T K I D E S G T I F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.7 97.4 58.7 N.A. 86.6 N.A. N.A. 49.5 49.2 N.A. 51.8 N.A. N.A. N.A. N.A. 31.6
Protein Similarity: 100 74.7 99.3 63.5 N.A. 95.5 N.A. N.A. 59.1 61.5 N.A. 70 N.A. N.A. N.A. N.A. 49.6
P-Site Identity: 100 100 93.3 100 N.A. 80 N.A. N.A. 33.3 26.6 N.A. 33.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. 60 46.6 N.A. 40 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 12 0 0 0 0 0 0 78 0 0 0 % A
% Cys: 0 12 0 0 0 56 0 0 0 0 0 0 0 0 0 % C
% Asp: 34 0 0 0 0 0 89 0 100 0 0 0 0 0 45 % D
% Glu: 0 56 0 0 0 0 0 0 0 12 0 0 12 23 12 % E
% Phe: 0 0 0 67 0 12 0 0 0 45 12 0 0 0 12 % F
% Gly: 0 0 0 12 0 0 0 0 0 0 0 12 0 56 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 12 0 0 0 12 0 12 0 0 0 12 0 % I
% Lys: 12 0 0 0 56 0 12 0 0 0 0 0 0 12 23 % K
% Leu: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 56 0 12 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % Q
% Arg: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 23 0 23 0 12 0 0 89 0 0 12 0 12 0 0 % S
% Thr: 0 12 12 0 0 12 0 0 0 0 0 0 78 0 0 % T
% Val: 0 12 0 12 0 12 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 0 0 0 34 78 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _