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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RFESD All Species: 27.27
Human Site: S29 Identified Species: 75
UniProt: Q8TAC1 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TAC1 NP_001124537.1 157 17762 S29 R E D D I K K S E R M T A V V
Chimpanzee Pan troglodytes XP_001136313 210 23700 S82 R E D D I K K S E R M T A V V
Rhesus Macaque Macaca mulatta XP_001093050 158 17858 S29 R E D D I K K S E R M T A V V
Dog Lupus familis XP_546019 233 26102 S104 R E E D I K K S E R M T A V V
Cat Felis silvestris
Mouse Mus musculus Q8K2P6 157 17948 S29 R E E D I R K S E R M T A V V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508796 240 26609 S105 R E A D I K K S E R I T S M V
Chicken Gallus gallus XP_424710 187 21234 S57 K E D D I K K S Q R I T A K V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_688339 160 17836 I33 A R R V V K S I G G R D V L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789096 161 18396 S30 A F Y L Y D W S D P D Q K W K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.7 97.4 58.7 N.A. 86.6 N.A. N.A. 49.5 49.2 N.A. 51.8 N.A. N.A. N.A. N.A. 31.6
Protein Similarity: 100 74.7 99.3 63.5 N.A. 95.5 N.A. N.A. 59.1 61.5 N.A. 70 N.A. N.A. N.A. N.A. 49.6
P-Site Identity: 100 100 100 93.3 N.A. 86.6 N.A. N.A. 73.3 73.3 N.A. 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 93.3 93.3 N.A. 26.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 0 12 0 0 0 0 0 0 0 0 0 67 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 45 78 0 12 0 0 12 0 12 12 0 0 0 % D
% Glu: 0 78 23 0 0 0 0 0 67 0 0 0 0 0 0 % E
% Phe: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 12 12 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 78 0 0 12 0 0 23 0 0 0 0 % I
% Lys: 12 0 0 0 0 78 78 0 0 0 0 0 12 12 12 % K
% Leu: 0 0 0 12 0 0 0 0 0 0 0 0 0 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 56 0 0 12 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 12 0 0 12 0 0 0 % Q
% Arg: 67 12 12 0 0 12 0 0 0 78 12 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 12 89 0 0 0 0 12 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 78 0 0 0 % T
% Val: 0 0 0 12 12 0 0 0 0 0 0 0 12 56 89 % V
% Trp: 0 0 0 0 0 0 12 0 0 0 0 0 0 12 0 % W
% Tyr: 0 0 12 0 12 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _