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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RFESD All Species: 22.73
Human Site: T121 Identified Species: 62.5
UniProt: Q8TAC1 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TAC1 NP_001124537.1 157 17762 T121 G I K Q R I H T V T V D N G N
Chimpanzee Pan troglodytes XP_001136313 210 23700 T174 G I K Q R I H T V T V D N G N
Rhesus Macaque Macaca mulatta XP_001093050 158 17858 T121 G V K Q R I H T V T V D N G N
Dog Lupus familis XP_546019 233 26102 K196 G V K Q R I H K V T V D N G S
Cat Felis silvestris
Mouse Mus musculus Q8K2P6 157 17948 T121 G V K Q R I H T V K V D N G N
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508796 240 26609 T197 G V K Q R I H T V T V K N G N
Chicken Gallus gallus XP_424710 187 21234 K149 G E K Q R I H K V T V K N K N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_688339 160 17836 T118 G I K Q R I H T V T E S N G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789096 161 18396 S116 K W S I D L T S G E V K S P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.7 97.4 58.7 N.A. 86.6 N.A. N.A. 49.5 49.2 N.A. 51.8 N.A. N.A. N.A. N.A. 31.6
Protein Similarity: 100 74.7 99.3 63.5 N.A. 95.5 N.A. N.A. 59.1 61.5 N.A. 70 N.A. N.A. N.A. N.A. 49.6
P-Site Identity: 100 100 93.3 80 N.A. 86.6 N.A. N.A. 86.6 73.3 N.A. 80 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 N.A. N.A. 93.3 73.3 N.A. 86.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 12 0 0 0 0 0 0 56 0 0 12 % D
% Glu: 0 12 0 0 0 0 0 0 0 12 12 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 89 0 0 0 0 0 0 0 12 0 0 0 0 78 0 % G
% His: 0 0 0 0 0 0 89 0 0 0 0 0 0 0 0 % H
% Ile: 0 34 0 12 0 89 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 0 89 0 0 0 0 23 0 12 0 34 0 12 12 % K
% Leu: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 89 0 67 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % P
% Gln: 0 0 0 89 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 89 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 12 0 0 0 0 12 0 0 0 12 12 0 12 % S
% Thr: 0 0 0 0 0 0 12 67 0 78 0 0 0 0 0 % T
% Val: 0 45 0 0 0 0 0 0 89 0 89 0 0 0 0 % V
% Trp: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _