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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC6
All Species:
32.73
Human Site:
S520
Identified Species:
60
UniProt:
Q8TAG9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TAG9
NP_001013870.1
804
93722
S520
I
D
D
M
L
R
K
S
T
N
L
L
L
T
R
Chimpanzee
Pan troglodytes
XP_507926
929
107221
S640
I
D
D
M
L
R
K
S
T
N
L
L
L
T
R
Rhesus Macaque
Macaca mulatta
XP_001088450
925
107094
S641
I
D
D
M
L
R
K
S
T
N
L
L
L
T
R
Dog
Lupus familis
XP_849326
798
93237
S514
I
D
D
M
L
R
K
S
T
N
L
L
L
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R313
802
93058
S518
I
D
D
M
L
R
K
S
T
N
L
L
L
T
R
Rat
Rattus norvegicus
O54923
804
93159
S520
I
D
D
M
L
R
K
S
T
N
L
L
L
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506370
1098
124562
S814
I
D
D
M
L
R
K
S
T
N
L
L
L
T
R
Chicken
Gallus gallus
NP_001012923
761
88650
S483
L
L
L
T
R
T
L
S
S
C
L
Q
N
L
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE6
766
88707
A492
V
A
A
M
V
R
K
A
A
N
L
L
L
T
R
Honey Bee
Apis mellifera
XP_393572
765
88660
S483
I
D
E
M
I
C
K
S
T
N
L
L
L
T
R
Nematode Worm
Caenorhab. elegans
Q18286
817
93860
C541
V
D
D
T
V
R
R
C
A
N
V
L
L
G
R
Sea Urchin
Strong. purpuratus
XP_001197185
648
74903
V382
L
H
I
K
N
L
V
V
L
F
V
Q
T
V
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXX6
789
89851
K506
V
L
R
K
Y
L
D
K
I
L
I
D
V
L
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
86.1
94
N.A.
92.1
93
N.A.
64.3
84.1
N.A.
N.A.
N.A.
41.1
51.2
38.3
44
Protein Similarity:
100
86.4
86.4
95.4
N.A.
95.7
96.6
N.A.
68.9
88.8
N.A.
N.A.
N.A.
63
69.6
60.9
57.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
13.3
N.A.
N.A.
N.A.
60
80
46.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
26.6
N.A.
N.A.
N.A.
80
93.3
73.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
8
16
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
8
0
8
0
0
0
0
0
% C
% Asp:
0
70
62
0
0
0
8
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
62
0
8
0
8
0
0
0
8
0
8
0
0
0
8
% I
% Lys:
0
0
0
16
0
0
70
8
0
0
0
0
0
0
0
% K
% Leu:
16
16
8
0
54
16
8
0
8
8
77
77
77
16
0
% L
% Met:
0
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
77
0
0
8
0
16
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% Q
% Arg:
0
0
8
0
8
70
8
0
0
0
0
0
0
0
77
% R
% Ser:
0
0
0
0
0
0
0
70
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
16
0
8
0
0
62
0
0
0
8
70
0
% T
% Val:
24
0
0
0
16
0
8
8
0
0
16
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _