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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC6
All Species:
14.55
Human Site:
T258
Identified Species:
26.67
UniProt:
Q8TAG9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TAG9
NP_001013870.1
804
93722
T258
I
P
E
E
R
N
E
T
V
L
K
H
S
L
E
Chimpanzee
Pan troglodytes
XP_507926
929
107221
T378
I
P
E
E
R
N
E
T
V
L
K
H
S
L
E
Rhesus Macaque
Macaca mulatta
XP_001088450
925
107094
T379
I
P
E
E
R
N
E
T
V
L
K
H
S
L
E
Dog
Lupus familis
XP_849326
798
93237
E253
P
E
E
R
K
E
N
E
L
K
Q
G
F
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R313
802
93058
V256
I
L
E
E
K
S
D
V
I
P
K
H
A
L
E
Rat
Rattus norvegicus
O54923
804
93159
I258
T
L
E
E
K
S
D
I
I
L
K
H
T
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506370
1098
124562
P553
L
D
E
G
K
E
V
P
S
K
Q
T
L
E
E
Chicken
Gallus gallus
NP_001012923
761
88650
T229
E
H
D
E
E
V
L
T
A
Q
D
L
V
D
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE6
766
88707
G230
E
H
M
Q
Q
M
N
G
G
E
A
G
G
A
G
Honey Bee
Apis mellifera
XP_393572
765
88660
S226
I
G
R
K
K
K
R
S
H
V
T
N
S
N
E
Nematode Worm
Caenorhab. elegans
Q18286
817
93860
N280
D
G
S
I
V
K
K
N
M
S
P
K
R
N
M
Sea Urchin
Strong. purpuratus
XP_001197185
648
74903
T128
A
T
V
D
H
L
Q
T
C
L
P
V
L
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXX6
789
89851
T245
R
R
A
E
E
Q
N
T
G
G
L
G
E
L
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
86.1
94
N.A.
92.1
93
N.A.
64.3
84.1
N.A.
N.A.
N.A.
41.1
51.2
38.3
44
Protein Similarity:
100
86.4
86.4
95.4
N.A.
95.7
96.6
N.A.
68.9
88.8
N.A.
N.A.
N.A.
63
69.6
60.9
57.8
P-Site Identity:
100
100
100
13.3
N.A.
46.6
46.6
N.A.
13.3
13.3
N.A.
N.A.
N.A.
0
20
0
13.3
P-Site Similarity:
100
100
100
33.3
N.A.
80
80
N.A.
33.3
20
N.A.
N.A.
N.A.
13.3
53.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
8
0
8
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
8
8
8
0
0
16
0
0
0
8
0
0
8
0
% D
% Glu:
16
8
54
54
16
16
24
8
0
8
0
0
8
24
62
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% F
% Gly:
0
16
0
8
0
0
0
8
16
8
0
24
8
0
8
% G
% His:
0
16
0
0
8
0
0
0
8
0
0
39
0
0
0
% H
% Ile:
39
0
0
8
0
0
0
8
16
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
39
16
8
0
0
16
39
8
0
0
0
% K
% Leu:
8
16
0
0
0
8
8
0
8
39
8
8
16
47
0
% L
% Met:
0
0
8
0
0
8
0
0
8
0
0
0
0
0
16
% M
% Asn:
0
0
0
0
0
24
24
8
0
0
0
8
0
16
0
% N
% Pro:
8
24
0
0
0
0
0
8
0
8
16
0
0
0
0
% P
% Gln:
0
0
0
8
8
8
8
0
0
8
16
0
0
0
0
% Q
% Arg:
8
8
8
8
24
0
8
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
8
0
0
16
0
8
8
8
0
0
31
0
0
% S
% Thr:
8
8
0
0
0
0
0
47
0
0
8
8
8
0
0
% T
% Val:
0
0
8
0
8
8
8
8
24
8
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _