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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EXOC6 All Species: 31.82
Human Site: T757 Identified Species: 58.33
UniProt: Q8TAG9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TAG9 NP_001013870.1 804 93722 T757 V N P N T A L T L L E K M K D
Chimpanzee Pan troglodytes XP_507926 929 107221 T877 V N P N T A L T L L E N R V Y
Rhesus Macaque Macaca mulatta XP_001088450 925 107094 T878 V N P N T A L T L L E K M K D
Dog Lupus familis XP_849326 798 93237 T751 V N P N T A L T L L E K M K D
Cat Felis silvestris
Mouse Mus musculus Q8R313 802 93058 T755 V N P H A A L T L L E K M K D
Rat Rattus norvegicus O54923 804 93159 T757 V N P H A A L T L L E K M K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506370 1098 124562 T1051 V N P S T A L T I L E R M K D
Chicken Gallus gallus NP_001012923 761 88650 T710 V N P S T A L T L L E K V H R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VDE6 766 88707 V725 V Q P Q S I I V I L E K I R E
Honey Bee Apis mellifera XP_393572 765 88660 L720 V T P N M A V L L L E K L K E
Nematode Worm Caenorhab. elegans Q18286 817 93860 V778 V K A S T A I V V L E K M I E
Sea Urchin Strong. purpuratus XP_001197185 648 74903 E609 T Y D W S L D E S A G R A S G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXX6 789 89851 T748 L D Y K K V A T I C E K F K D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.2 86.1 94 N.A. 92.1 93 N.A. 64.3 84.1 N.A. N.A. N.A. 41.1 51.2 38.3 44
Protein Similarity: 100 86.4 86.4 95.4 N.A. 95.7 96.6 N.A. 68.9 88.8 N.A. N.A. N.A. 63 69.6 60.9 57.8
P-Site Identity: 100 73.3 100 100 N.A. 86.6 86.6 N.A. 80 73.3 N.A. N.A. N.A. 33.3 60 46.6 0
P-Site Similarity: 100 73.3 100 100 N.A. 93.3 93.3 N.A. 100 86.6 N.A. N.A. N.A. 73.3 80 73.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 25.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 16 77 8 0 0 8 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 8 8 0 0 0 8 0 0 0 0 0 0 0 54 % D
% Glu: 0 0 0 0 0 0 0 8 0 0 93 0 0 0 24 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % G
% His: 0 0 0 16 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 8 16 0 24 0 0 0 8 8 0 % I
% Lys: 0 8 0 8 8 0 0 0 0 0 0 77 0 62 0 % K
% Leu: 8 0 0 0 0 8 62 8 62 85 0 0 8 0 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 54 0 0 % M
% Asn: 0 62 0 39 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 77 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 16 8 8 8 % R
% Ser: 0 0 0 24 16 0 0 0 8 0 0 0 0 8 0 % S
% Thr: 8 8 0 0 54 0 0 70 0 0 0 0 0 0 0 % T
% Val: 85 0 0 0 0 8 8 16 8 0 0 0 8 8 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _