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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC6
All Species:
30.61
Human Site:
Y305
Identified Species:
56.11
UniProt:
Q8TAG9
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TAG9
NP_001013870.1
804
93722
Y305
D
E
E
T
F
E
N
Y
Y
R
K
Q
R
K
K
Chimpanzee
Pan troglodytes
XP_507926
929
107221
Y425
D
E
E
T
F
E
N
Y
Y
R
K
Q
R
K
K
Rhesus Macaque
Macaca mulatta
XP_001088450
925
107094
Y426
D
E
E
T
F
E
N
Y
Y
R
K
Q
R
K
K
Dog
Lupus familis
XP_849326
798
93237
Y300
E
E
T
F
E
N
Y
Y
R
K
Q
R
K
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8R313
802
93058
Y303
D
E
E
T
F
E
N
Y
Y
R
K
Q
R
K
K
Rat
Rattus norvegicus
O54923
804
93159
Y305
D
E
E
T
F
E
N
Y
Y
R
K
Q
R
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506370
1098
124562
Y600
E
E
T
F
E
N
Y
Y
R
K
Q
R
K
K
Q
Chicken
Gallus gallus
NP_001012923
761
88650
S276
L
V
L
Q
P
Q
S
S
M
H
E
T
V
E
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE6
766
88707
D277
Q
R
E
Y
F
E
K
D
Y
R
Q
Q
R
R
D
Honey Bee
Apis mellifera
XP_393572
765
88660
R273
K
A
Y
Y
R
Q
Q
R
K
Q
Q
A
R
L
V
Nematode Worm
Caenorhab. elegans
Q18286
817
93860
Y327
A
K
E
E
F
E
Q
Y
Y
R
Q
Q
R
K
E
Sea Urchin
Strong. purpuratus
XP_001197185
648
74903
M175
R
Y
R
F
C
E
R
M
A
D
N
I
P
M
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXX6
789
89851
Y292
V
P
E
R
F
R
D
Y
Y
Y
E
N
R
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
86.1
94
N.A.
92.1
93
N.A.
64.3
84.1
N.A.
N.A.
N.A.
41.1
51.2
38.3
44
Protein Similarity:
100
86.4
86.4
95.4
N.A.
95.7
96.6
N.A.
68.9
88.8
N.A.
N.A.
N.A.
63
69.6
60.9
57.8
P-Site Identity:
100
100
100
20
N.A.
100
100
N.A.
20
0
N.A.
N.A.
N.A.
46.6
6.6
60
6.6
P-Site Similarity:
100
100
100
60
N.A.
100
100
N.A.
60
26.6
N.A.
N.A.
N.A.
60
26.6
80
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
8
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
39
0
0
0
0
0
8
8
0
8
0
0
0
0
8
% D
% Glu:
16
54
62
8
16
62
0
0
0
0
16
0
0
8
8
% E
% Phe:
0
0
0
24
62
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% I
% Lys:
8
8
0
0
0
0
8
0
8
16
39
0
16
62
39
% K
% Leu:
8
0
8
0
0
0
0
0
0
0
0
0
0
16
8
% L
% Met:
0
0
0
0
0
0
0
8
8
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
16
39
0
0
0
8
8
0
0
0
% N
% Pro:
0
8
0
0
8
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
8
0
0
8
0
16
16
0
0
8
39
54
0
0
16
% Q
% Arg:
8
8
8
8
8
8
8
8
16
54
0
16
70
8
0
% R
% Ser:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
16
39
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
8
8
0
0
0
0
0
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
16
0
0
16
70
62
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _