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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC6
All Species:
40.91
Human Site:
Y424
Identified Species:
75
UniProt:
Q8TAG9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TAG9
NP_001013870.1
804
93722
Y424
L
F
E
I
R
D
Q
Y
N
E
T
L
L
K
K
Chimpanzee
Pan troglodytes
XP_507926
929
107221
Y544
L
F
E
I
R
D
Q
Y
N
E
T
L
L
K
K
Rhesus Macaque
Macaca mulatta
XP_001088450
925
107094
Y545
L
F
E
I
R
D
Q
Y
N
E
T
L
L
K
K
Dog
Lupus familis
XP_849326
798
93237
Y418
L
F
E
I
R
D
Q
Y
N
E
T
L
L
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R313
802
93058
Y422
L
F
E
I
R
D
Q
Y
N
E
T
L
L
K
K
Rat
Rattus norvegicus
O54923
804
93159
Y424
L
F
E
I
R
D
Q
Y
N
E
T
L
L
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506370
1098
124562
Y718
L
F
E
I
R
E
Q
Y
G
E
T
L
L
K
K
Chicken
Gallus gallus
NP_001012923
761
88650
R390
K
K
W
S
G
L
F
R
D
I
F
E
A
D
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE6
766
88707
Y396
L
H
N
M
R
D
H
Y
N
E
V
L
L
Q
R
Honey Bee
Apis mellifera
XP_393572
765
88660
Y387
L
Q
E
I
R
V
H
Y
N
E
V
L
M
Q
H
Nematode Worm
Caenorhab. elegans
Q18286
817
93860
Y445
L
Q
N
F
R
D
Q
Y
N
E
I
L
V
K
E
Sea Urchin
Strong. purpuratus
XP_001197185
648
74903
S289
G
E
R
E
V
F
E
S
Y
Y
R
K
Q
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXX6
789
89851
Y410
L
D
K
S
R
D
K
Y
H
E
L
L
L
E
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
86.1
94
N.A.
92.1
93
N.A.
64.3
84.1
N.A.
N.A.
N.A.
41.1
51.2
38.3
44
Protein Similarity:
100
86.4
86.4
95.4
N.A.
95.7
96.6
N.A.
68.9
88.8
N.A.
N.A.
N.A.
63
69.6
60.9
57.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
0
N.A.
N.A.
N.A.
53.3
53.3
60
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
6.6
N.A.
N.A.
N.A.
73.3
66.6
73.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
70
0
0
8
0
0
0
0
8
0
% D
% Glu:
0
8
62
8
0
8
8
0
0
85
0
8
0
8
16
% E
% Phe:
0
54
0
8
0
8
8
0
0
0
8
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
16
0
8
0
0
0
0
0
8
% H
% Ile:
0
0
0
62
0
0
0
0
0
8
8
0
0
0
0
% I
% Lys:
8
8
8
0
0
0
8
0
0
0
0
8
0
62
54
% K
% Leu:
85
0
0
0
0
8
0
0
0
0
8
85
70
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
16
0
0
0
0
0
70
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
16
0
0
0
0
62
0
0
0
0
0
8
16
0
% Q
% Arg:
0
0
8
0
85
0
0
8
0
0
8
0
0
8
8
% R
% Ser:
0
0
0
16
0
0
0
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
54
0
0
0
8
% T
% Val:
0
0
0
0
8
8
0
0
0
0
16
0
8
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _