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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC6
All Species:
33.64
Human Site:
Y456
Identified Species:
61.67
UniProt:
Q8TAG9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TAG9
NP_001013870.1
804
93722
Y456
P
V
V
N
E
E
E
Y
K
I
V
I
S
K
F
Chimpanzee
Pan troglodytes
XP_507926
929
107221
Y576
P
V
V
N
E
E
E
Y
K
I
V
I
S
K
F
Rhesus Macaque
Macaca mulatta
XP_001088450
925
107094
Y577
P
I
V
N
E
E
E
Y
K
I
V
I
S
K
F
Dog
Lupus familis
XP_849326
798
93237
Y450
P
I
V
N
E
E
E
Y
K
A
V
I
S
K
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8R313
802
93058
Y454
P
I
G
S
E
E
E
Y
K
V
V
I
S
R
F
Rat
Rattus norvegicus
O54923
804
93159
Y456
P
I
G
S
E
E
E
Y
K
M
V
I
S
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506370
1098
124562
Y750
P
V
A
N
E
E
E
Y
K
I
I
I
S
R
F
Chicken
Gallus gallus
NP_001012923
761
88650
Q419
V
I
S
K
F
P
F
Q
D
S
E
L
D
K
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE6
766
88707
Y428
V
V
Q
N
T
E
E
Y
E
C
I
I
E
R
F
Honey Bee
Apis mellifera
XP_393572
765
88660
Y419
H
V
T
T
Q
E
E
Y
D
N
V
L
D
L
F
Nematode Worm
Caenorhab. elegans
Q18286
817
93860
F477
T
V
N
S
E
E
E
F
R
T
I
I
R
K
F
Sea Urchin
Strong. purpuratus
XP_001197185
648
74903
K318
D
S
L
D
H
Y
K
K
Y
F
H
Q
I
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXX6
789
89851
Y442
V
I
K
K
E
A
D
Y
E
N
N
V
L
S
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
86.1
94
N.A.
92.1
93
N.A.
64.3
84.1
N.A.
N.A.
N.A.
41.1
51.2
38.3
44
Protein Similarity:
100
86.4
86.4
95.4
N.A.
95.7
96.6
N.A.
68.9
88.8
N.A.
N.A.
N.A.
63
69.6
60.9
57.8
P-Site Identity:
100
100
93.3
86.6
N.A.
66.6
73.3
N.A.
80
6.6
N.A.
N.A.
N.A.
46.6
40
46.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
20
N.A.
N.A.
N.A.
66.6
53.3
73.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
0
8
0
16
0
0
0
16
0
0
% D
% Glu:
0
0
0
0
70
77
77
0
16
0
8
0
8
0
0
% E
% Phe:
0
0
0
0
8
0
8
8
0
8
0
0
0
0
85
% F
% Gly:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
8
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
47
0
0
0
0
0
0
0
31
24
70
8
0
0
% I
% Lys:
0
0
8
16
0
0
8
8
54
0
0
0
0
54
0
% K
% Leu:
0
0
8
0
0
0
0
0
0
0
0
16
8
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
8
47
0
0
0
0
0
16
8
0
0
0
0
% N
% Pro:
54
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
8
0
0
8
0
0
0
8
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
8
24
0
% R
% Ser:
0
8
8
24
0
0
0
0
0
8
0
0
54
8
0
% S
% Thr:
8
0
8
8
8
0
0
0
0
8
0
0
0
0
0
% T
% Val:
24
47
31
0
0
0
0
0
0
8
54
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
77
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _