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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC8 All Species: 18.18
Human Site: Y251 Identified Species: 44.44
UniProt: Q8TAM2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TAM2 NP_653197.2 531 60392 Y251 K V Q I G K C Y Y R L G M Y R
Chimpanzee Pan troglodytes XP_001139331 531 60388 Y251 K V Q I G K C Y Y R L G M Y R
Rhesus Macaque Macaca mulatta XP_001086901 531 60343 Y251 K V Q I G K C Y Y R L G M Y R
Dog Lupus familis XP_537534 531 60211 Y251 K V Q I G K C Y Y R L G M Y R
Cat Felis silvestris
Mouse Mus musculus Q8VD72 515 58421 Y235 K V Q I G K C Y Y R L G M Y R
Rat Rattus norvegicus NP_001100222 441 50585 D183 E L F S K A L D L A S L S T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507260 500 56654 Q240 F K S A L K Q Q E M V D T F L
Chicken Gallus gallus XP_421311 567 64065 F287 K V Q I G K C F Y R L G L Y R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001035399 507 57281 Q247 F R S A L A Q Q E F V D T H L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785839 500 56328 Q240 F K S A M K Q Q E G I D V Y L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.8 93.7 N.A. 91.1 75.7 N.A. 81.7 75.4 N.A. 73 N.A. N.A. N.A. N.A. 66.2
Protein Similarity: 100 100 99.8 96.6 N.A. 93.7 80.2 N.A. 87.3 84.6 N.A. 84.5 N.A. N.A. N.A. N.A. 81.7
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 6.6 86.6 N.A. 0 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 20 100 N.A. 13.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 30 0 20 0 0 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 60 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 0 0 30 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 30 0 0 0 0 0 10 % E
% Phe: 30 0 10 0 0 0 0 10 0 10 0 0 0 10 0 % F
% Gly: 0 0 0 0 60 0 0 0 0 10 0 60 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 60 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 60 20 0 0 10 80 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 20 0 10 0 10 0 60 10 10 0 30 % L
% Met: 0 0 0 0 10 0 0 0 0 10 0 0 50 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 60 0 0 0 30 30 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 60 0 0 0 0 60 % R
% Ser: 0 0 30 10 0 0 0 0 0 0 10 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 20 10 0 % T
% Val: 0 60 0 0 0 0 0 0 0 0 20 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 60 0 0 0 0 70 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _