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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPLOC4 All Species: 20
Human Site: Y462 Identified Species: 29.33
UniProt: Q8TAT6 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TAT6 NP_060391.2 608 68120 Y462 T F P K D P V Y T F S I S Q N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001111288 217 24313 T72 F P K D P V Y T F S I S Q N P
Dog Lupus familis XP_540482 615 68578 Y469 T F P K D P V Y T F S I S Q N
Cat Felis silvestris
Mouse Mus musculus P60670 608 67999 Y462 T F P K D P V Y T F S I S Q N
Rat Rattus norvegicus Q9ES54 608 68038 Y462 T F P K D P V Y T F S I S Q N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519304 502 54514 T357 K F V T A V A T G G P D N Q V
Chicken Gallus gallus XP_415704 677 76245 S463 G W A K S S Q S T A R S S E G
Frog Xenopus laevis NP_001080427 610 68598 Y464 T F P K D P V Y T F S T S S N
Zebra Danio Brachydanio rerio NP_956101 624 69608 F478 T F P K D P V F T F S S T F R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VBP9 652 73343 F498 P L Q P I Y T F T E Y D K R Q
Honey Bee Apis mellifera XP_393332 646 73569 F481 P L T P Q F T F H I S N T I T
Nematode Worm Caenorhab. elegans NP_495093 529 59592 V384 S K S A K F N V E N R Q A I G
Sea Urchin Strong. purpuratus XP_789485 627 69736 F478 P K D A T F A F N S Q P G L K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82264 413 46151 E268 G G A D V H F E A F Q M S D M
Baker's Yeast Sacchar. cerevisiae P33755 580 65764 D430 A Y I N D T T D E R Y V P E I
Red Bread Mold Neurospora crassa Q7SH49 651 73094 R496 H G F P E S P R P V F T N D G
Conservation
Percent
Protein Identity: 100 N.A. 35.5 96 N.A. 97.3 97 N.A. 67.9 70.3 87.3 81.5 N.A. 46.4 51 38.8 55.5
Protein Similarity: 100 N.A. 35.5 97.2 N.A. 98.5 98.5 N.A. 71 77.4 93.9 88.9 N.A. 63.9 67.9 56.5 70.4
P-Site Identity: 100 N.A. 0 100 N.A. 100 100 N.A. 13.3 20 86.6 66.6 N.A. 6.6 6.6 0 0
P-Site Similarity: 100 N.A. 0 100 N.A. 100 100 N.A. 20 33.3 86.6 80 N.A. 20 20 13.3 6.6
Percent
Protein Identity: N.A. N.A. N.A. 23.8 33.5 32.1
Protein Similarity: N.A. N.A. N.A. 38.9 55.4 49.4
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 0
P-Site Similarity: N.A. N.A. N.A. 20 26.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 13 13 7 0 13 0 7 7 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 13 44 0 0 7 0 0 0 13 0 13 0 % D
% Glu: 0 0 0 0 7 0 0 7 13 7 0 0 0 13 0 % E
% Phe: 7 44 7 0 0 19 7 25 7 44 7 0 0 7 0 % F
% Gly: 13 13 0 0 0 0 0 0 7 7 0 0 7 0 19 % G
% His: 7 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 7 0 0 0 0 7 7 25 0 13 7 % I
% Lys: 7 13 7 44 7 0 0 0 0 0 0 0 7 0 7 % K
% Leu: 0 13 0 0 0 0 0 0 0 0 0 0 0 7 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % M
% Asn: 0 0 0 7 0 0 7 0 7 7 0 7 13 7 32 % N
% Pro: 19 7 38 19 7 38 7 0 7 0 7 7 7 0 7 % P
% Gln: 0 0 7 0 7 0 7 0 0 0 13 7 7 32 7 % Q
% Arg: 0 0 0 0 0 0 0 7 0 7 13 0 0 7 7 % R
% Ser: 7 0 7 0 7 13 0 7 0 13 44 19 44 7 0 % S
% Thr: 38 0 7 7 7 7 19 13 50 0 0 13 13 0 7 % T
% Val: 0 0 7 0 7 13 38 7 0 7 0 7 0 0 7 % V
% Trp: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 7 7 32 0 0 13 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _