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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX2-3
All Species:
4.55
Human Site:
Y72
Identified Species:
9.09
UniProt:
Q8TAU0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TAU0
NP_660328.2
364
38406
Y72
D
E
G
E
K
L
S
Y
L
N
S
L
A
A
A
Chimpanzee
Pan troglodytes
XP_001166828
293
32446
L20
S
V
K
D
I
L
N
L
E
Q
Q
H
Q
H
F
Rhesus Macaque
Macaca mulatta
XP_001106216
296
32619
Q23
D
I
L
N
L
E
Q
Q
Q
Q
H
F
H
G
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97334
362
38072
Y71
E
E
G
E
K
L
S
Y
L
N
S
L
A
A
A
Rat
Rattus norvegicus
O35767
318
34318
C45
A
T
L
A
P
A
S
C
M
L
A
A
F
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513144
199
22401
Chicken
Gallus gallus
Q90788
294
33054
E20
V
K
D
I
L
N
L
E
Q
Q
Q
Q
G
G
L
Frog
Xenopus laevis
P42583
299
34079
L26
L
E
Q
H
Q
S
G
L
S
P
M
D
I
T
S
Zebra Danio
Brachydanio rerio
Q90481
269
30288
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015473
468
50968
L171
N
P
Y
A
M
G
T
L
Y
H
S
P
G
V
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NLC2
299
33058
E26
E
E
T
G
I
D
E
E
K
S
S
E
D
D
C
Sea Urchin
Strong. purpuratus
XP_783123
344
37966
M64
C
G
L
Q
E
D
C
M
L
P
D
P
G
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.7
76.9
N.A.
N.A.
90.6
45.3
N.A.
43.4
46.4
43.9
32.4
N.A.
26.9
N.A.
25.5
30.2
Protein Similarity:
100
78.8
78.5
N.A.
N.A.
93.1
54.1
N.A.
46.9
57.4
56.8
43.1
N.A.
39.5
N.A.
34.3
43.9
P-Site Identity:
100
6.6
13.3
N.A.
N.A.
93.3
6.6
N.A.
0
0
6.6
0
N.A.
6.6
N.A.
13.3
6.6
P-Site Similarity:
100
20
13.3
N.A.
N.A.
100
20
N.A.
0
6.6
20
0
N.A.
26.6
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
17
0
9
0
0
0
0
9
9
17
17
25
% A
% Cys:
9
0
0
0
0
0
9
9
0
0
0
0
0
0
9
% C
% Asp:
17
0
9
9
0
17
0
0
0
0
9
9
9
9
0
% D
% Glu:
17
34
0
17
9
9
9
17
9
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
9
% F
% Gly:
0
9
17
9
0
9
9
0
0
0
0
0
25
17
0
% G
% His:
0
0
0
9
0
0
0
0
0
9
9
9
9
9
0
% H
% Ile:
0
9
0
9
17
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
9
9
0
17
0
0
0
9
0
0
0
0
9
0
% K
% Leu:
9
0
25
0
17
25
9
25
25
9
0
17
0
0
9
% L
% Met:
0
0
0
0
9
0
0
9
9
0
9
0
0
0
9
% M
% Asn:
9
0
0
9
0
9
9
0
0
17
0
0
0
0
0
% N
% Pro:
0
9
0
0
9
0
0
0
0
17
0
17
0
0
9
% P
% Gln:
0
0
9
9
9
0
9
9
17
25
17
9
9
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
9
25
0
9
9
34
0
0
9
9
% S
% Thr:
0
9
9
0
0
0
9
0
0
0
0
0
0
9
0
% T
% Val:
9
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
17
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _