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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM76A
All Species:
20.91
Human Site:
S161
Identified Species:
46
UniProt:
Q8TAV0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TAV0
NP_001137384.1
307
35049
S161
H
Q
E
K
E
Q
Y
S
R
L
S
G
G
G
H
Chimpanzee
Pan troglodytes
XP_001149482
282
32423
K144
Q
K
T
K
E
Q
R
K
H
L
S
S
S
S
R
Rhesus Macaque
Macaca mulatta
XP_001111954
341
38433
S195
H
Q
E
K
E
Q
Y
S
R
L
S
G
G
G
H
Dog
Lupus familis
XP_535343
306
35004
Y160
S
H
Q
E
K
E
Q
Y
R
L
S
G
G
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q922G2
307
35077
S161
H
Q
E
K
E
Q
Y
S
R
L
S
G
G
S
H
Rat
Rattus norvegicus
NP_001102156
307
35118
S161
H
Q
E
K
E
Q
Y
S
R
L
S
G
G
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505960
316
35634
S170
L
S
S
S
S
S
S
S
S
S
G
G
G
S
H
Chicken
Gallus gallus
Q5ZJ65
307
34902
S161
L
Q
E
K
E
Q
Y
S
R
L
S
S
G
S
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PBM7
328
37672
H181
H
R
H
G
S
S
H
H
K
I
S
G
N
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391846
329
36613
K168
Q
Q
R
A
A
K
H
K
E
Q
K
L
K
S
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785345
445
49005
E294
D
R
D
K
D
K
K
E
D
H
R
H
H
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.7
90
99
N.A.
98.3
97.3
N.A.
89.2
94.1
N.A.
69.5
N.A.
N.A.
46.5
N.A.
43.8
Protein Similarity:
100
83.3
90
99
N.A.
98.3
98
N.A.
93.3
96.7
N.A.
79.5
N.A.
N.A.
60.7
N.A.
55
P-Site Identity:
100
33.3
100
40
N.A.
93.3
93.3
N.A.
26.6
80
N.A.
20
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
40
100
66.6
N.A.
93.3
93.3
N.A.
26.6
80
N.A.
46.6
N.A.
N.A.
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
10
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
46
10
55
10
0
10
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
10
64
64
19
0
% G
% His:
46
10
10
0
0
0
19
10
10
10
0
10
10
0
73
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
10
0
64
10
19
10
19
10
0
10
0
10
10
0
% K
% Leu:
19
0
0
0
0
0
0
0
0
64
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
19
55
10
0
0
55
10
0
0
10
0
0
0
0
0
% Q
% Arg:
0
19
10
0
0
0
10
0
55
0
10
0
0
0
10
% R
% Ser:
10
10
10
10
19
19
10
55
10
10
73
19
10
64
19
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
46
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _