KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM76A
All Species:
21.52
Human Site:
T139
Identified Species:
47.33
UniProt:
Q8TAV0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TAV0
NP_001137384.1
307
35049
T139
Y
K
R
V
L
Q
K
T
K
E
Q
R
K
H
L
Chimpanzee
Pan troglodytes
XP_001149482
282
32423
K122
D
R
K
K
V
D
G
K
L
L
C
W
L
C
T
Rhesus Macaque
Macaca mulatta
XP_001111954
341
38433
T173
Y
K
R
V
L
Q
K
T
K
E
Q
R
K
H
L
Dog
Lupus familis
XP_535343
306
35004
K138
S
Y
K
R
V
L
Q
K
T
K
E
Q
R
K
H
Cat
Felis silvestris
Mouse
Mus musculus
Q922G2
307
35077
T139
Y
K
R
V
L
Q
K
T
K
E
Q
R
K
H
L
Rat
Rattus norvegicus
NP_001102156
307
35118
T139
Y
K
R
V
L
Q
K
T
R
E
Q
R
K
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505960
316
35634
S148
E
Q
R
K
H
L
S
S
S
A
R
A
G
Q
P
Chicken
Gallus gallus
Q5ZJ65
307
34902
T139
Y
K
R
V
L
Q
K
T
K
E
Q
C
K
H
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PBM7
328
37672
L159
S
H
S
N
S
S
S
L
S
E
K
E
H
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391846
329
36613
T146
Y
K
R
A
L
A
K
T
K
Q
S
D
A
E
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785345
445
49005
G272
D
R
D
R
G
G
G
G
E
K
D
R
D
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.7
90
99
N.A.
98.3
97.3
N.A.
89.2
94.1
N.A.
69.5
N.A.
N.A.
46.5
N.A.
43.8
Protein Similarity:
100
83.3
90
99
N.A.
98.3
98
N.A.
93.3
96.7
N.A.
79.5
N.A.
N.A.
60.7
N.A.
55
P-Site Identity:
100
0
100
0
N.A.
100
93.3
N.A.
6.6
93.3
N.A.
6.6
N.A.
N.A.
46.6
N.A.
6.6
P-Site Similarity:
100
20
100
46.6
N.A.
100
100
N.A.
26.6
93.3
N.A.
13.3
N.A.
N.A.
53.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
0
0
0
10
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
0
% C
% Asp:
19
0
10
0
0
10
0
0
0
0
10
10
10
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
10
55
10
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
19
10
0
0
0
0
10
0
0
% G
% His:
0
10
0
0
10
0
0
0
0
0
0
0
10
46
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
55
19
19
0
0
55
19
46
19
10
0
46
10
0
% K
% Leu:
0
0
0
0
55
19
0
10
10
10
0
0
10
0
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
10
0
0
0
46
10
0
0
10
46
10
0
19
0
% Q
% Arg:
0
19
64
19
0
0
0
0
10
0
10
46
10
10
19
% R
% Ser:
19
0
10
0
10
10
19
10
19
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
55
10
0
0
0
0
0
19
% T
% Val:
0
0
0
46
19
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
55
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _