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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM76A
All Species:
25.76
Human Site:
T174
Identified Species:
56.67
UniProt:
Q8TAV0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TAV0
NP_001137384.1
307
35049
T174
G
H
Y
N
S
Q
K
T
L
S
T
S
S
I
Q
Chimpanzee
Pan troglodytes
XP_001149482
282
32423
K157
S
R
A
G
H
Q
E
K
E
Q
Y
S
R
L
S
Rhesus Macaque
Macaca mulatta
XP_001111954
341
38433
T208
G
H
Y
N
S
Q
K
T
L
S
T
S
S
I
Q
Dog
Lupus familis
XP_535343
306
35004
T173
S
H
Y
N
S
Q
K
T
L
S
T
S
S
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q922G2
307
35077
T174
S
H
Y
N
S
Q
K
T
L
S
T
S
S
I
Q
Rat
Rattus norvegicus
NP_001102156
307
35118
T174
S
H
Y
N
S
Q
K
T
L
S
T
S
S
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505960
316
35634
T183
S
H
Y
N
S
Q
K
T
L
S
T
S
S
I
Q
Chicken
Gallus gallus
Q5ZJ65
307
34902
T174
S
H
Y
N
S
Q
K
T
L
S
T
S
S
I
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PBM7
328
37672
G194
L
S
P
E
Q
D
Q
G
L
W
K
Q
S
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391846
329
36613
R181
S
H
N
K
R
P
H
R
I
D
V
T
K
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785345
445
49005
K307
K
S
K
A
N
D
K
K
Q
T
L
H
E
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.7
90
99
N.A.
98.3
97.3
N.A.
89.2
94.1
N.A.
69.5
N.A.
N.A.
46.5
N.A.
43.8
Protein Similarity:
100
83.3
90
99
N.A.
98.3
98
N.A.
93.3
96.7
N.A.
79.5
N.A.
N.A.
60.7
N.A.
55
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
26.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
26.6
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
33.3
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
19
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
10
0
10
0
0
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
73
0
0
10
0
10
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
73
0
% I
% Lys:
10
0
10
10
0
0
73
19
0
0
10
0
10
0
0
% K
% Leu:
10
0
0
0
0
0
0
0
73
0
10
0
0
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
64
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
10
0
0
0
0
0
0
0
10
10
% P
% Gln:
0
0
0
0
10
73
10
0
10
10
0
10
0
0
73
% Q
% Arg:
0
10
0
0
10
0
0
10
0
0
0
0
10
0
0
% R
% Ser:
64
19
0
0
64
0
0
0
0
64
0
73
73
0
10
% S
% Thr:
0
0
0
0
0
0
0
64
0
10
64
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
64
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _