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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP2W1
All Species:
16.36
Human Site:
T401
Identified Species:
40
UniProt:
Q8TAV3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TAV3
NP_060251.2
490
53844
T401
L
D
E
T
Q
W
Q
T
P
G
Q
F
N
P
G
Chimpanzee
Pan troglodytes
XP_518926
490
53979
T401
L
D
E
T
Q
W
Q
T
P
G
Q
F
N
P
G
Rhesus Macaque
Macaca mulatta
Q6GUQ4
493
56626
P404
L
Y
D
N
Q
E
F
P
D
P
E
K
F
K
P
Dog
Lupus familis
XP_548722
501
55102
T401
L
D
K
T
Q
W
E
T
P
R
Q
F
N
P
G
Cat
Felis silvestris
Mouse
Mus musculus
P56656
490
55884
P402
L
H
D
S
K
E
F
P
N
P
E
L
F
D
P
Rat
Rattus norvegicus
P05179
490
56169
P402
L
H
D
S
K
E
F
P
N
P
E
M
F
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511639
621
70856
T532
L
D
K
S
Q
W
E
T
P
N
V
F
N
P
N
Chicken
Gallus gallus
XP_414762
504
56768
T404
L
D
K
T
Q
W
E
T
P
D
E
F
N
P
N
Frog
Xenopus laevis
NP_001083248
492
56361
K406
Y
D
Q
T
H
F
E
K
P
H
E
F
Y
P
Q
Zebra Danio
Brachydanio rerio
XP_692555
504
57153
K415
K
D
E
S
E
W
E
K
P
N
S
F
Y
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
37.9
82.8
N.A.
41
38.3
N.A.
48.1
54.1
40.8
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
59.4
89.2
N.A.
61.4
60
N.A.
58.7
72
61.7
60.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
80
N.A.
6.6
6.6
N.A.
60
66.6
33.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
93.3
N.A.
33.3
33.3
N.A.
80
86.6
60
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
70
30
0
0
0
0
0
10
10
0
0
0
20
0
% D
% Glu:
0
0
30
0
10
30
50
0
0
0
50
0
0
0
10
% E
% Phe:
0
0
0
0
0
10
30
0
0
0
0
70
30
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
30
% G
% His:
0
20
0
0
10
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
30
0
20
0
0
20
0
0
0
10
0
10
0
% K
% Leu:
80
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
20
20
0
0
50
0
20
% N
% Pro:
0
0
0
0
0
0
0
30
70
30
0
0
0
70
30
% P
% Gln:
0
0
10
0
60
0
20
0
0
0
30
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
0
40
0
0
0
0
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
50
0
0
0
50
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
0
0
0
0
0
0
0
0
0
20
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _