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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PUM2 All Species: 31.21
Human Site: S592 Identified Species: 76.3
UniProt: Q8TB72 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TB72 NP_056132.1 1066 114216 S592 R E S L S T S S D L Y K R S S
Chimpanzee Pan troglodytes XP_001140509 1065 114143 S593 R E S L S T S S D L Y K R S S
Rhesus Macaque Macaca mulatta XP_001095741 1065 114189 S593 R E S L S T S S D L Y K R S S
Dog Lupus familis XP_849088 1063 114024 S591 R E S L S T S S D L Y K R S S
Cat Felis silvestris
Mouse Mus musculus Q80U58 1066 114295 S592 R E S L S T S S D L Y K R S S
Rat Rattus norvegicus NP_001100185 1061 113778 S593 R E S L S T S S D L Y K R S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q2VB19 1189 126658 S715 R D S L T G S S D L Y K R T S
Frog Xenopus laevis NP_001081119 1190 127467 S716 R D S L T G S S D I Y K R T S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25822 1533 157510 N969 Y G A L G A G N A S A S P L G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q07807 879 98049 K460 N N S N N A N K Q A N P Y L E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.3 98.5 N.A. 97.7 97.2 N.A. N.A. 71.1 69.4 N.A. N.A. 31 N.A. N.A. N.A.
Protein Similarity: 100 99.7 99.5 99 N.A. 98.8 98.4 N.A. N.A. 77.1 75.3 N.A. N.A. 42.2 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 73.3 66.6 N.A. N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 93.3 N.A. N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 20 0 0 10 10 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 20 0 0 0 0 0 0 80 0 0 0 0 0 0 % D
% Glu: 0 60 0 0 0 0 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 10 20 10 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 0 80 0 0 0 % K
% Leu: 0 0 0 90 0 0 0 0 0 70 0 0 0 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 0 10 10 0 10 10 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 80 0 0 0 0 0 0 0 0 0 0 0 80 0 0 % R
% Ser: 0 0 90 0 60 0 80 80 0 10 0 10 0 60 80 % S
% Thr: 0 0 0 0 20 60 0 0 0 0 0 0 0 20 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 80 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _