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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITFG1
All Species:
22.12
Human Site:
S308
Identified Species:
48.67
UniProt:
Q8TB96
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TB96
NP_110417.2
612
68108
S308
V
P
V
L
Q
D
F
S
N
K
G
T
L
W
G
Chimpanzee
Pan troglodytes
XP_520622
612
68049
S308
V
P
V
L
Q
D
F
S
N
K
G
T
L
W
G
Rhesus Macaque
Macaca mulatta
XP_001114075
612
68027
S308
V
P
V
L
Q
D
F
S
N
K
G
T
L
W
G
Dog
Lupus familis
XP_851471
613
68086
S309
I
P
V
L
Q
E
F
S
N
K
G
T
L
W
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99KW9
610
67457
S306
V
P
V
L
Q
D
F
S
N
K
G
T
L
W
G
Rat
Rattus norvegicus
Q8R4E1
610
67318
S306
A
P
V
L
Q
D
S
S
N
K
G
T
L
W
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507399
549
61495
M278
L
H
I
G
D
Y
N
M
D
G
Y
P
D
A
L
Chicken
Gallus gallus
NP_001005840
602
66779
R298
I
P
V
L
Q
D
F
R
N
K
D
T
L
W
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391877
596
66657
V295
D
K
W
Y
N
L
K
V
N
F
R
D
G
D
N
Nematode Worm
Caenorhab. elegans
P30639
599
67574
K293
T
Q
M
A
S
W
S
K
T
K
L
W
G
L
V
Sea Urchin
Strong. purpuratus
XP_785844
561
62121
V285
D
F
T
V
L
P
L
V
A
R
T
G
D
F
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
94.7
N.A.
89
87.2
N.A.
76.6
77.7
N.A.
N.A.
N.A.
N.A.
38.5
27.4
33
Protein Similarity:
100
99.6
99.5
97
N.A.
93.7
93.3
N.A.
82.3
84.8
N.A.
N.A.
N.A.
N.A.
55.5
45.4
50
P-Site Identity:
100
100
100
86.6
N.A.
100
86.6
N.A.
0
80
N.A.
N.A.
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
20
86.6
N.A.
N.A.
N.A.
N.A.
6.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
0
10
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
0
10
55
0
0
10
0
10
10
19
10
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
55
0
0
10
0
0
0
10
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
10
55
10
19
0
64
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
19
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
10
10
0
73
0
0
0
0
0
% K
% Leu:
10
0
0
64
10
10
10
0
0
0
10
0
64
10
10
% L
% Met:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
10
0
73
0
0
0
0
0
19
% N
% Pro:
0
64
0
0
0
10
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
10
0
0
64
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
10
10
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
19
55
0
0
0
0
0
0
0
% S
% Thr:
10
0
10
0
0
0
0
0
10
0
10
64
0
0
0
% T
% Val:
37
0
64
10
0
0
0
19
0
0
0
0
0
0
10
% V
% Trp:
0
0
10
0
0
10
0
0
0
0
0
10
0
64
0
% W
% Tyr:
0
0
0
10
0
10
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _