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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITFG1
All Species:
26.97
Human Site:
S489
Identified Species:
59.33
UniProt:
Q8TB96
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TB96
NP_110417.2
612
68108
S489
N
G
S
A
G
Q
L
S
Q
S
A
H
L
A
L
Chimpanzee
Pan troglodytes
XP_520622
612
68049
S489
N
G
S
A
G
Q
L
S
Q
S
A
H
L
A
L
Rhesus Macaque
Macaca mulatta
XP_001114075
612
68027
S489
N
G
S
A
G
Q
L
S
Q
S
A
H
L
A
L
Dog
Lupus familis
XP_851471
613
68086
S490
N
G
S
A
G
Q
L
S
Q
S
A
H
L
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99KW9
610
67457
S487
N
G
S
A
G
Q
L
S
Q
S
A
H
L
A
L
Rat
Rattus norvegicus
Q8R4E1
610
67318
S487
N
G
S
A
G
Q
L
S
Q
S
A
H
L
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507399
549
61495
R458
H
L
F
V
G
I
P
R
P
L
G
E
K
T
I
Chicken
Gallus gallus
NP_001005840
602
66779
S479
N
G
S
A
G
Q
L
S
Q
S
A
H
F
A
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391877
596
66657
P480
N
A
I
A
A
Q
L
P
Q
S
A
H
F
S
L
Nematode Worm
Caenorhab. elegans
P30639
599
67574
P477
Q
S
V
A
C
Q
V
P
A
S
S
N
R
A
L
Sea Urchin
Strong. purpuratus
XP_785844
561
62121
G468
T
L
M
V
G
V
P
G
P
T
Q
E
G
T
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
94.7
N.A.
89
87.2
N.A.
76.6
77.7
N.A.
N.A.
N.A.
N.A.
38.5
27.4
33
Protein Similarity:
100
99.6
99.5
97
N.A.
93.7
93.3
N.A.
82.3
84.8
N.A.
N.A.
N.A.
N.A.
55.5
45.4
50
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
93.3
N.A.
N.A.
N.A.
N.A.
60
33.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
93.3
N.A.
N.A.
N.A.
N.A.
66.6
53.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
82
10
0
0
0
10
0
73
0
0
73
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
19
0
0
% F
% Gly:
0
64
0
0
82
0
0
10
0
0
10
0
10
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
73
0
0
0
% H
% Ile:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
19
0
0
0
0
73
0
0
10
0
0
55
0
82
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
73
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
19
19
19
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
82
0
0
73
0
10
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% R
% Ser:
0
10
64
0
0
0
0
64
0
82
10
0
0
10
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
10
0
0
0
19
0
% T
% Val:
0
0
10
19
0
10
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _