KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITFG1
All Species:
19.7
Human Site:
S523
Identified Species:
43.33
UniProt:
Q8TB96
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TB96
NP_110417.2
612
68108
S523
Y
V
G
I
P
R
P
S
G
E
K
S
I
R
K
Chimpanzee
Pan troglodytes
XP_520622
612
68049
S523
Y
V
G
I
P
R
P
S
G
E
K
S
I
R
K
Rhesus Macaque
Macaca mulatta
XP_001114075
612
68027
S523
Y
V
G
I
P
R
P
S
G
E
K
S
I
R
K
Dog
Lupus familis
XP_851471
613
68086
S524
Y
V
G
I
P
R
P
S
G
E
K
S
I
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99KW9
610
67457
P521
F
V
G
I
P
R
P
P
G
E
K
S
I
R
K
Rat
Rattus norvegicus
Q8R4E1
610
67318
S521
F
V
G
I
P
R
P
S
G
E
K
S
I
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507399
549
61495
W492
P
H
N
V
P
R
S
W
S
A
K
L
Y
L
T
Chicken
Gallus gallus
NP_001005840
602
66779
L513
Y
V
G
I
P
R
P
L
G
E
K
S
I
R
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391877
596
66657
S514
T
I
G
V
G
G
K
S
R
E
W
P
Q
I
I
Nematode Worm
Caenorhab. elegans
P30639
599
67574
A511
N
I
A
I
P
K
Y
A
D
R
K
E
D
W
K
Sea Urchin
Strong. purpuratus
XP_785844
561
62121
N502
P
D
P
L
D
K
P
N
D
W
I
S
K
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
94.7
N.A.
89
87.2
N.A.
76.6
77.7
N.A.
N.A.
N.A.
N.A.
38.5
27.4
33
Protein Similarity:
100
99.6
99.5
97
N.A.
93.7
93.3
N.A.
82.3
84.8
N.A.
N.A.
N.A.
N.A.
55.5
45.4
50
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
20
86.6
N.A.
N.A.
N.A.
N.A.
20
26.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
26.6
93.3
N.A.
N.A.
N.A.
N.A.
33.3
46.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
10
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
0
0
0
19
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
73
0
10
0
0
0
% E
% Phe:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
73
0
10
10
0
0
64
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
0
73
0
0
0
0
0
0
10
0
64
19
10
% I
% Lys:
0
0
0
0
0
19
10
0
0
0
82
0
10
0
64
% K
% Leu:
0
0
0
10
0
0
0
10
0
0
0
10
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
19
0
10
0
82
0
73
10
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
73
0
0
10
10
0
0
0
64
10
% R
% Ser:
0
0
0
0
0
0
10
55
10
0
0
73
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
64
0
19
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
10
10
0
0
10
0
% W
% Tyr:
46
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _