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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHDC4 All Species: 31.52
Human Site: S232 Identified Species: 57.78
UniProt: Q8TBB5 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBB5 NP_060036.2 520 57892 S232 G T G P T P R S G C Q M S V T
Chimpanzee Pan troglodytes XP_001157133 541 60088 S232 G T G P T P R S G C Q M S V T
Rhesus Macaque Macaca mulatta XP_001086874 522 58135 S232 G T G P T P R S G C Q M S V T
Dog Lupus familis XP_546788 667 72888 S341 G A G P T P R S G C Q M S V T
Cat Felis silvestris
Mouse Mus musculus Q921I2 584 64842 S232 G A G P T P R S G C L M A V T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508869 624 70162 S277 G P G P T P R S G C Q M S A T
Chicken Gallus gallus NP_001025749 579 65046 S232 G I G P A P R S G C Q M A T T
Frog Xenopus laevis NP_001079516 578 65206 S232 G T A P L P R S G C Q M I T N
Zebra Danio Brachydanio rerio NP_001119902 585 65979 S232 G T G P C P R S A C Q M T P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648590 509 56333 I232 K A E I G G A I V P S P R S G
Honey Bee Apis mellifera XP_624296 469 54330 H196 L V I F G G F H D N L K D Y K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SDM9 470 51651 V197 P I D K H L Y V F D L E T R T
Baker's Yeast Sacchar. cerevisiae Q08979 651 75415 G253 S K P D A R S G H C F I P T D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.3 95.7 63.2 N.A. 72.7 N.A. N.A. 62.1 69 64.3 63.4 N.A. 41.1 41.5 N.A. N.A.
Protein Similarity: 100 94.6 97.5 70.9 N.A. 79.4 N.A. N.A. 72.4 79.2 76.1 74 N.A. 59.6 58.4 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 80 N.A. N.A. 86.6 73.3 66.6 73.3 N.A. 0 0 N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 N.A. N.A. 86.6 80 66.6 80 N.A. 0 0 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.5 27.3 N.A.
Protein Similarity: N.A. N.A. N.A. 35.7 41.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 8 0 16 0 8 0 8 0 0 0 16 8 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 77 0 0 0 0 0 % C
% Asp: 0 0 8 8 0 0 0 0 8 8 0 0 8 0 8 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 8 0 0 8 0 8 0 8 0 0 0 0 % F
% Gly: 70 0 62 0 16 16 0 8 62 0 0 0 0 0 8 % G
% His: 0 0 0 0 8 0 0 8 8 0 0 0 0 0 0 % H
% Ile: 0 16 8 8 0 0 0 8 0 0 0 8 8 0 0 % I
% Lys: 8 8 0 8 0 0 0 0 0 0 0 8 0 0 8 % K
% Leu: 8 0 0 0 8 8 0 0 0 0 24 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 70 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % N
% Pro: 8 8 8 70 0 70 0 0 0 8 0 8 8 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 62 0 0 0 0 % Q
% Arg: 0 0 0 0 0 8 70 0 0 0 0 0 8 8 0 % R
% Ser: 8 0 0 0 0 0 8 70 0 0 8 0 39 8 0 % S
% Thr: 0 39 0 0 47 0 0 0 0 0 0 0 16 24 70 % T
% Val: 0 8 0 0 0 0 0 8 8 0 0 0 0 39 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _