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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHKBP1
All Species:
22.73
Human Site:
S418
Identified Species:
55.56
UniProt:
Q8TBC3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBC3
NP_612401.2
707
76344
S418
Q
H
P
E
T
V
G
S
G
P
Q
L
F
Q
T
Chimpanzee
Pan troglodytes
XP_512668
707
76127
S418
Q
H
P
E
T
V
G
S
G
P
Q
L
F
Q
T
Rhesus Macaque
Macaca mulatta
XP_001091454
632
68096
F348
V
G
S
G
P
Q
L
F
Q
T
F
T
V
H
R
Dog
Lupus familis
XP_533665
702
75670
S418
Q
H
P
E
T
V
G
S
G
P
Q
L
F
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6P7W2
704
76085
S418
Q
H
P
E
T
V
G
S
G
P
Q
L
F
Q
T
Rat
Rattus norvegicus
P0C5J9
704
75954
S418
Q
H
P
E
T
V
G
S
G
P
Q
L
F
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510454
817
89351
S409
Q
H
P
E
T
V
G
S
G
P
Q
L
F
Q
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649952
730
80149
D421
L
Y
K
D
V
T
L
D
P
I
T
A
I
S
V
Honey Bee
Apis mellifera
XP_394892
690
76665
D396
P
L
R
M
K
D
N
D
L
L
V
T
E
L
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784158
652
71962
V369
I
V
Q
H
P
E
T
V
G
Q
G
P
Q
L
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
88.1
95
N.A.
92.7
91.8
N.A.
57.1
N.A.
N.A.
N.A.
N.A.
48
51
N.A.
51
Protein Similarity:
100
97.4
88.2
96.1
N.A.
94.4
93.7
N.A.
67
N.A.
N.A.
N.A.
N.A.
65.8
68.3
N.A.
64.6
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
13.3
0
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
0
20
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
60
0
10
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
10
0
60
0
10
% F
% Gly:
0
10
0
10
0
0
60
0
70
0
10
0
0
0
0
% G
% His:
0
60
0
10
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% I
% Lys:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
0
0
0
20
0
10
10
0
60
0
20
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
60
0
20
0
0
0
10
60
0
10
0
0
0
% P
% Gln:
60
0
10
0
0
10
0
0
10
10
60
0
10
60
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
0
10
0
0
0
0
60
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
60
10
10
0
0
10
10
20
0
0
60
% T
% Val:
10
10
0
0
10
60
0
10
0
0
10
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _