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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM22
All Species:
22.73
Human Site:
S247
Identified Species:
62.5
UniProt:
Q8TBE7
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBE7
NP_001091069.1
412
46450
S247
N
I
V
D
E
D
N
S
L
L
N
A
W
K
E
Chimpanzee
Pan troglodytes
Q0Q7U8
338
35052
Q181
G
P
G
L
W
T
L
Q
E
G
T
M
G
V
Y
Rhesus Macaque
Macaca mulatta
XP_001114866
412
46443
S247
N
I
V
D
E
D
N
S
L
L
N
A
W
K
E
Dog
Lupus familis
XP_542795
412
46490
S247
N
I
V
D
E
D
N
S
L
L
N
A
W
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5F297
340
35554
Q183
G
P
G
L
G
T
L
Q
E
G
T
T
G
L
Y
Rat
Rattus norvegicus
Q5M7A3
412
46577
S247
N
I
A
D
E
D
N
S
L
L
N
V
W
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509687
414
45717
S249
N
L
A
D
D
G
N
S
S
P
G
A
W
K
A
Chicken
Gallus gallus
Q5ZJZ4
411
45722
S246
N
I
V
K
E
E
N
S
L
L
S
T
W
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013581
413
45554
S247
N
I
A
D
E
E
K
S
A
L
G
F
W
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.7
98.5
97.3
N.A.
25.7
91.9
N.A.
81.1
78.1
N.A.
72.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
43.4
99.2
98.5
N.A.
44.6
96.1
N.A.
89.1
86.4
N.A.
83
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
0
86.6
N.A.
46.6
73.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
100
100
N.A.
0
86.6
N.A.
60
86.6
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
0
0
0
0
0
12
0
0
45
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
67
12
45
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
67
23
0
0
23
0
0
0
0
0
67
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
23
0
23
0
12
12
0
0
0
23
23
0
23
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
0
0
12
0
0
0
0
0
0
78
0
% K
% Leu:
0
12
0
23
0
0
23
0
56
67
0
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
78
0
0
0
0
0
67
0
0
0
45
0
0
0
0
% N
% Pro:
0
23
0
0
0
0
0
0
0
12
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
23
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
78
12
0
12
0
0
0
0
% S
% Thr:
0
0
0
0
0
23
0
0
0
0
23
23
0
0
0
% T
% Val:
0
0
45
0
0
0
0
0
0
0
0
12
0
12
0
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
0
0
78
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _