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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM81A
All Species:
29.09
Human Site:
S259
Identified Species:
80
UniProt:
Q8TBF8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBF8
NP_689663.2
365
42017
S259
S
L
I
V
K
E
N
S
G
A
S
E
R
D
M
Chimpanzee
Pan troglodytes
XP_001172927
377
43336
S271
S
L
I
V
K
E
N
S
G
A
S
E
R
D
M
Rhesus Macaque
Macaca mulatta
XP_001099041
365
41999
S259
S
L
I
V
K
E
N
S
G
A
S
E
R
D
M
Dog
Lupus familis
XP_535501
365
41996
S259
S
L
V
V
K
E
N
S
G
A
S
E
R
D
M
Cat
Felis silvestris
Mouse
Mus musculus
Q3UXZ6
364
41691
S259
S
L
I
V
K
E
N
S
G
A
N
E
R
D
V
Rat
Rattus norvegicus
NP_001101633
364
41837
S259
S
L
I
V
K
E
N
S
G
A
S
E
R
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516589
532
60301
S420
S
L
I
V
K
E
N
S
E
I
S
E
R
I
I
Chicken
Gallus gallus
XP_413781
382
43835
T271
S
L
T
F
K
E
N
T
E
M
S
E
R
A
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787187
368
42130
M256
R
S
K
R
D
K
R
M
D
E
M
E
D
T
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
99.7
93.1
N.A.
92.5
93.6
N.A.
58.4
66.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
27.1
Protein Similarity:
100
96.5
100
98
N.A.
97.5
97.5
N.A.
63.7
80.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
50.5
P-Site Identity:
100
100
100
93.3
N.A.
86.6
100
N.A.
73.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
80
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
67
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
0
0
12
0
0
0
12
67
0
% D
% Glu:
0
0
0
0
0
89
0
0
23
12
0
100
0
0
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
67
0
0
0
0
0
0
12
0
0
0
12
12
% I
% Lys:
0
0
12
0
89
12
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
89
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
12
0
12
12
0
0
0
56
% M
% Asn:
0
0
0
0
0
0
89
0
0
0
12
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
12
0
0
12
0
0
0
0
0
89
0
0
% R
% Ser:
89
12
0
0
0
0
0
78
0
0
78
0
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
12
0
0
0
0
0
12
12
% T
% Val:
0
0
12
78
0
0
0
0
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _