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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGXT2L1
All Species:
12.59
Human Site:
S494
Identified Species:
18.46
UniProt:
Q8TBG4
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBG4
NP_001140062.1
499
55671
S494
T
D
T
H
S
L
L
S
K
R
L
K
T
_
_
Chimpanzee
Pan troglodytes
XP_001137764
499
55702
S494
T
D
T
H
S
L
L
S
K
R
L
K
T
_
_
Rhesus Macaque
Macaca mulatta
XP_001087348
499
55544
S494
A
D
T
H
S
L
L
S
K
R
L
K
T
_
_
Dog
Lupus familis
XP_535690
497
55971
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWU8
499
55478
S494
S
D
Q
Q
A
L
L
S
K
R
L
K
T
_
_
Rat
Rattus norvegicus
Q64565
512
57182
F499
V
D
F
A
F
E
V
F
R
S
A
L
T
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518449
556
61343
Chicken
Gallus gallus
XP_426301
505
55954
P499
Y
P
E
K
H
S
V
P
S
K
T
I
R
T
_
Frog
Xenopus laevis
Q6DEB1
509
56952
L495
A
Y
R
Q
S
N
G
L
H
P
E
S
P
T
F
Zebra Danio
Brachydanio rerio
Q7SY54
492
54717
K487
T
S
T
I
P
L
S
K
K
T
K
R
N
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU95
494
54265
Honey Bee
Apis mellifera
XP_392348
482
53855
K477
K
S
T
C
P
S
V
K
P
L
L
V
R
_
_
Nematode Worm
Caenorhab. elegans
P91408
467
51626
E453
F
N
E
N
N
I
L
E
T
V
T
A
L
D
Q
Sea Urchin
Strong. purpuratus
XP_001187418
531
59206
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940M2
476
51934
D467
D
D
A
D
F
L
V
D
A
L
D
Y
S
I
S
Baker's Yeast
Sacchar. cerevisiae
P07991
424
46067
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.1
74.5
N.A.
83.9
35.5
N.A.
68.8
72.6
71.9
66.1
N.A.
52.5
54.9
44.4
49.3
Protein Similarity:
100
99.4
97.5
81.7
N.A.
92.1
51.5
N.A.
76.4
84.5
85.2
80.9
N.A.
70.1
73.5
62.5
66.2
P-Site Identity:
100
100
92.3
0
N.A.
69.2
13.3
N.A.
0
0
6.6
30.7
N.A.
0
15.3
6.6
0
P-Site Similarity:
100
100
92.3
0
N.A.
84.6
26.6
N.A.
0
14.2
6.6
38.4
N.A.
0
23
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.6
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.9
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
7
7
7
0
0
0
7
0
7
7
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
38
0
7
0
0
0
7
0
0
7
0
0
7
0
% D
% Glu:
0
0
13
0
0
7
0
7
0
0
7
0
0
0
0
% E
% Phe:
7
0
7
0
13
0
0
7
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
19
7
0
0
0
7
0
0
0
0
0
7
% H
% Ile:
0
0
0
7
0
7
0
0
0
0
0
7
0
7
0
% I
% Lys:
7
0
0
7
0
0
0
13
32
7
7
25
0
0
0
% K
% Leu:
0
0
0
0
0
38
32
7
0
13
32
7
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
7
7
7
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
7
0
0
13
0
0
7
7
7
0
0
7
0
0
% P
% Gln:
0
0
7
13
0
0
0
0
0
0
0
0
0
7
7
% Q
% Arg:
0
0
7
0
0
0
0
0
7
25
0
7
13
0
0
% R
% Ser:
7
13
0
0
25
13
7
25
7
7
0
7
7
0
7
% S
% Thr:
19
0
32
0
0
0
0
0
7
7
13
0
32
13
0
% T
% Val:
7
0
0
0
0
0
25
0
0
7
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
38
44
% _