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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGXT2L1 All Species: 36.97
Human Site: T98 Identified Species: 54.22
UniProt: Q8TBG4 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBG4 NP_001140062.1 499 55671 T98 Y A K R L S A T L P E K L S V
Chimpanzee Pan troglodytes XP_001137764 499 55702 T98 Y A K R L S A T L P E K L S V
Rhesus Macaque Macaca mulatta XP_001087348 499 55544 T98 Y A K R L S A T L P E K L S V
Dog Lupus familis XP_535690 497 55971 T126 Y Y V Y I L W T I M Q T L K I
Cat Felis silvestris
Mouse Mus musculus Q8BWU8 499 55478 T98 F A K R L T A T L P Q E L S V
Rat Rattus norvegicus Q64565 512 57182 V124 C H P K V T A V A K K Q M D R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518449 556 61343 T157 Y A K R L S A T L P E K L S V
Chicken Gallus gallus XP_426301 505 55954 T102 Y A Q R L T A T L P E K L S V
Frog Xenopus laevis Q6DEB1 509 56952 T98 Y A E C L I S T L P E K L S V
Zebra Danio Brachydanio rerio Q7SY54 492 54717 T99 Y A Q R L Q A T L P E K L S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VU95 494 54265 K109 C A R T L T S K M P E P L S V
Honey Bee Apis mellifera XP_392348 482 53855 L101 C A R R L T S L L P E P L S V
Nematode Worm Caenorhab. elegans P91408 467 51626 L94 V E A I S K Q L A T S T C N V
Sea Urchin Strong. purpuratus XP_001187418 531 59206 T101 Y A Q R L T Q T L P D K L N T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q940M2 476 51934 Q87 N I V E G K M Q Y L Y D E S G
Baker's Yeast Sacchar. cerevisiae P07991 424 46067 L69 H P H I I K A L T E Q A Q T L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.1 74.5 N.A. 83.9 35.5 N.A. 68.8 72.6 71.9 66.1 N.A. 52.5 54.9 44.4 49.3
Protein Similarity: 100 99.4 97.5 81.7 N.A. 92.1 51.5 N.A. 76.4 84.5 85.2 80.9 N.A. 70.1 73.5 62.5 66.2
P-Site Identity: 100 100 100 20 N.A. 73.3 6.6 N.A. 100 86.6 73.3 86.6 N.A. 46.6 60 6.6 60
P-Site Similarity: 100 100 100 46.6 N.A. 100 46.6 N.A. 100 100 86.6 93.3 N.A. 73.3 80 13.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. 40.6 25 N.A.
Protein Similarity: N.A. N.A. N.A. 55.9 43.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 69 7 0 0 0 57 0 13 0 0 7 0 0 0 % A
% Cys: 19 0 0 7 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 7 7 0 7 0 % D
% Glu: 0 7 7 7 0 0 0 0 0 7 57 7 7 0 0 % E
% Phe: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 7 % G
% His: 7 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 13 13 7 0 0 7 0 0 0 0 0 7 % I
% Lys: 0 0 32 7 0 19 0 7 0 7 7 50 0 7 0 % K
% Leu: 0 0 0 0 69 7 0 19 63 7 0 0 75 0 7 % L
% Met: 0 0 0 0 0 0 7 0 7 7 0 0 7 0 0 % M
% Asn: 7 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % N
% Pro: 0 7 7 0 0 0 0 0 0 69 0 13 0 0 0 % P
% Gln: 0 0 19 0 0 7 13 7 0 0 19 7 7 0 0 % Q
% Arg: 0 0 13 57 0 0 0 0 0 0 0 0 0 0 7 % R
% Ser: 0 0 0 0 7 25 19 0 0 0 7 0 0 69 0 % S
% Thr: 0 0 0 7 0 38 0 63 7 7 0 13 0 7 7 % T
% Val: 7 0 13 0 7 0 0 7 0 0 0 0 0 0 69 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 57 7 0 7 0 0 0 0 7 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _