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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGXT2L1
All Species:
35.15
Human Site:
Y174
Identified Species:
51.56
UniProt:
Q8TBG4
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBG4
NP_001140062.1
499
55671
Y174
V
A
P
T
P
D
T
Y
R
G
K
Y
R
E
D
Chimpanzee
Pan troglodytes
XP_001137764
499
55702
Y174
V
A
P
T
P
D
T
Y
R
G
K
Y
R
E
D
Rhesus Macaque
Macaca mulatta
XP_001087348
499
55544
Y174
V
A
P
T
P
D
T
Y
R
G
K
Y
R
E
D
Dog
Lupus familis
XP_535690
497
55971
Y205
V
A
P
A
P
D
T
Y
R
G
K
Y
R
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWU8
499
55478
Y174
V
A
P
A
P
D
T
Y
R
G
K
Y
R
E
D
Rat
Rattus norvegicus
Q64565
512
57182
L203
H
G
C
S
P
Y
T
L
G
L
T
N
V
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518449
556
61343
Y233
V
A
P
P
P
D
T
Y
Q
G
M
Y
R
E
D
Chicken
Gallus gallus
XP_426301
505
55954
Y179
V
A
P
S
P
D
I
Y
R
G
K
Y
R
E
D
Frog
Xenopus laevis
Q6DEB1
509
56952
Y175
V
A
P
S
P
D
T
Y
R
G
K
Y
R
E
D
Zebra Danio
Brachydanio rerio
Q7SY54
492
54717
Y176
V
A
L
S
P
D
T
Y
R
G
K
Y
R
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU95
494
54265
K189
C
P
D
V
Y
G
G
K
F
T
D
K
M
Y
P
Honey Bee
Apis mellifera
XP_392348
482
53855
K181
C
P
D
V
Y
R
G
K
Y
R
E
I
D
Y
P
Nematode Worm
Caenorhab. elegans
P91408
467
51626
T163
H
A
Y
H
G
H
V
T
T
T
M
E
L
S
P
Sea Urchin
Strong. purpuratus
XP_001187418
531
59206
T177
H
V
A
P
V
P
D
T
Y
R
G
K
Y
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940M2
476
51934
L154
A
A
K
M
P
G
N
L
K
V
V
Y
F
V
N
Baker's Yeast
Sacchar. cerevisiae
P07991
424
46067
A136
K
N
I
P
Q
D
K
A
I
I
L
G
A
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.1
74.5
N.A.
83.9
35.5
N.A.
68.8
72.6
71.9
66.1
N.A.
52.5
54.9
44.4
49.3
Protein Similarity:
100
99.4
97.5
81.7
N.A.
92.1
51.5
N.A.
76.4
84.5
85.2
80.9
N.A.
70.1
73.5
62.5
66.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
80
86.6
93.3
86.6
N.A.
0
0
6.6
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
20
N.A.
86.6
93.3
100
93.3
N.A.
0
6.6
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.6
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.9
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
69
7
13
0
0
0
7
0
0
0
0
7
0
0
% A
% Cys:
13
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
0
63
7
0
0
0
7
0
7
0
63
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
7
7
0
63
0
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% F
% Gly:
0
7
0
0
7
13
13
0
7
57
7
7
0
7
7
% G
% His:
19
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
7
0
7
7
0
7
0
0
7
% I
% Lys:
7
0
7
0
0
0
7
13
7
0
50
13
0
0
0
% K
% Leu:
0
0
7
0
0
0
0
13
0
7
7
0
7
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
13
0
7
0
0
% M
% Asn:
0
7
0
0
0
0
7
0
0
0
0
7
0
0
7
% N
% Pro:
0
13
50
19
69
7
0
0
0
0
0
0
0
0
19
% P
% Gln:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
7
0
0
50
13
0
0
57
7
0
% R
% Ser:
0
0
0
25
0
0
0
0
0
0
0
0
0
7
0
% S
% Thr:
0
0
0
19
0
0
57
13
7
13
7
0
0
0
0
% T
% Val:
57
7
0
13
7
0
7
0
0
7
7
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
13
7
0
57
13
0
0
63
7
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _