KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGXT2L1
All Species:
33.03
Human Site:
Y178
Identified Species:
48.44
UniProt:
Q8TBG4
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBG4
NP_001140062.1
499
55671
Y178
P
D
T
Y
R
G
K
Y
R
E
D
H
A
D
S
Chimpanzee
Pan troglodytes
XP_001137764
499
55702
Y178
P
D
T
Y
R
G
K
Y
R
E
D
H
A
D
P
Rhesus Macaque
Macaca mulatta
XP_001087348
499
55544
Y178
P
D
T
Y
R
G
K
Y
R
E
D
H
A
D
P
Dog
Lupus familis
XP_535690
497
55971
Y209
P
D
T
Y
R
G
K
Y
R
E
D
H
A
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWU8
499
55478
Y178
P
D
T
Y
R
G
K
Y
R
E
D
H
E
D
P
Rat
Rattus norvegicus
Q64565
512
57182
N207
P
Y
T
L
G
L
T
N
V
G
I
Y
K
M
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518449
556
61343
Y237
P
D
T
Y
Q
G
M
Y
R
E
D
H
P
D
P
Chicken
Gallus gallus
XP_426301
505
55954
Y183
P
D
I
Y
R
G
K
Y
R
E
D
H
P
D
P
Frog
Xenopus laevis
Q6DEB1
509
56952
Y179
P
D
T
Y
R
G
K
Y
R
E
D
H
P
D
P
Zebra Danio
Brachydanio rerio
Q7SY54
492
54717
Y180
P
D
T
Y
R
G
K
Y
R
E
D
H
P
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU95
494
54265
K193
Y
G
G
K
F
T
D
K
M
Y
P
D
A
D
M
Honey Bee
Apis mellifera
XP_392348
482
53855
I185
Y
R
G
K
Y
R
E
I
D
Y
P
K
E
D
L
Nematode Worm
Caenorhab. elegans
P91408
467
51626
E167
G
H
V
T
T
T
M
E
L
S
P
Y
K
F
D
Sea Urchin
Strong. purpuratus
XP_001187418
531
59206
K181
V
P
D
T
Y
R
G
K
Y
R
D
V
A
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940M2
476
51934
Y158
P
G
N
L
K
V
V
Y
F
V
N
S
G
S
E
Baker's Yeast
Sacchar. cerevisiae
P07991
424
46067
G140
Q
D
K
A
I
I
L
G
A
E
G
N
F
H
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.1
74.5
N.A.
83.9
35.5
N.A.
68.8
72.6
71.9
66.1
N.A.
52.5
54.9
44.4
49.3
Protein Similarity:
100
99.4
97.5
81.7
N.A.
92.1
51.5
N.A.
76.4
84.5
85.2
80.9
N.A.
70.1
73.5
62.5
66.2
P-Site Identity:
100
93.3
93.3
93.3
N.A.
86.6
13.3
N.A.
73.3
80
86.6
86.6
N.A.
13.3
6.6
0
13.3
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
86.6
20
N.A.
80
80
86.6
86.6
N.A.
13.3
13.3
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.6
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.9
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
7
0
0
0
38
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
63
7
0
0
0
7
0
7
0
63
7
0
69
7
% D
% Glu:
0
0
0
0
0
0
7
7
0
63
0
0
13
0
7
% E
% Phe:
0
0
0
0
7
0
0
0
7
0
0
0
7
7
0
% F
% Gly:
7
13
13
0
7
57
7
7
0
7
7
0
7
0
7
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
57
0
7
0
% H
% Ile:
0
0
7
0
7
7
0
7
0
0
7
0
0
0
0
% I
% Lys:
0
0
7
13
7
0
50
13
0
0
0
7
13
0
7
% K
% Leu:
0
0
0
13
0
7
7
0
7
0
0
0
0
0
7
% L
% Met:
0
0
0
0
0
0
13
0
7
0
0
0
0
7
7
% M
% Asn:
0
0
7
0
0
0
0
7
0
0
7
7
0
0
0
% N
% Pro:
69
7
0
0
0
0
0
0
0
0
19
0
25
0
50
% P
% Gln:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
0
50
13
0
0
57
7
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
7
0
7
0
7
7
% S
% Thr:
0
0
57
13
7
13
7
0
0
0
0
0
0
0
0
% T
% Val:
7
0
7
0
0
7
7
0
7
7
0
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
7
0
57
13
0
0
63
7
13
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _