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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGXT2L1
All Species:
41.82
Human Site:
Y189
Identified Species:
61.33
UniProt:
Q8TBG4
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBG4
NP_001140062.1
499
55671
Y189
H
A
D
S
A
S
A
Y
A
D
E
V
K
K
I
Chimpanzee
Pan troglodytes
XP_001137764
499
55702
Y189
H
A
D
P
A
S
A
Y
A
D
E
V
K
K
I
Rhesus Macaque
Macaca mulatta
XP_001087348
499
55544
Y189
H
A
D
P
A
S
A
Y
A
D
E
V
K
K
I
Dog
Lupus familis
XP_535690
497
55971
Y220
H
A
D
P
A
N
A
Y
A
D
E
V
K
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWU8
499
55478
Y189
H
E
D
P
S
T
A
Y
A
D
E
V
K
K
I
Rat
Rattus norvegicus
Q64565
512
57182
T218
Y
K
M
K
V
P
S
T
I
A
C
Q
S
T
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518449
556
61343
Y248
H
P
D
P
A
S
A
Y
A
D
E
V
K
K
I
Chicken
Gallus gallus
XP_426301
505
55954
Y194
H
P
D
P
A
S
A
Y
A
E
E
V
K
K
I
Frog
Xenopus laevis
Q6DEB1
509
56952
Y190
H
P
D
P
A
S
A
Y
A
K
D
V
E
D
I
Zebra Danio
Brachydanio rerio
Q7SY54
492
54717
Y191
H
P
D
P
A
T
A
Y
A
E
N
V
K
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU95
494
54265
Y204
D
A
D
M
G
A
L
Y
A
Q
P
I
E
E
I
Honey Bee
Apis mellifera
XP_392348
482
53855
Y196
K
E
D
L
G
V
K
Y
A
N
D
V
K
D
I
Nematode Worm
Caenorhab. elegans
P91408
467
51626
T178
Y
K
F
D
H
G
S
T
V
S
Q
P
D
W
V
Sea Urchin
Strong. purpuratus
XP_001187418
531
59206
Y192
V
A
V
A
G
V
K
Y
A
N
E
V
K
K
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940M2
476
51934
L169
S
G
S
E
A
N
E
L
A
M
M
M
A
R
L
Baker's Yeast
Sacchar. cerevisiae
P07991
424
46067
G151
N
F
H
G
R
T
F
G
A
I
S
L
S
T
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.1
74.5
N.A.
83.9
35.5
N.A.
68.8
72.6
71.9
66.1
N.A.
52.5
54.9
44.4
49.3
Protein Similarity:
100
99.4
97.5
81.7
N.A.
92.1
51.5
N.A.
76.4
84.5
85.2
80.9
N.A.
70.1
73.5
62.5
66.2
P-Site Identity:
100
93.3
93.3
80
N.A.
73.3
0
N.A.
86.6
80
60
53.3
N.A.
33.3
40
0
46.6
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
86.6
20
N.A.
86.6
86.6
73.3
80
N.A.
60
53.3
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.6
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.9
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
38
0
7
57
7
57
0
88
7
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
7
0
69
7
0
0
0
0
0
38
13
0
7
13
7
% D
% Glu:
0
13
0
7
0
0
7
0
0
13
50
0
13
19
0
% E
% Phe:
0
7
7
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
7
19
7
0
7
0
0
0
0
0
0
0
% G
% His:
57
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
7
0
7
0
0
63
% I
% Lys:
7
13
0
7
0
0
13
0
0
7
0
0
63
44
0
% K
% Leu:
0
0
0
7
0
0
7
7
0
0
0
7
0
0
7
% L
% Met:
0
0
7
7
0
0
0
0
0
7
7
7
0
0
7
% M
% Asn:
7
0
0
0
0
13
0
0
0
13
7
0
0
0
0
% N
% Pro:
0
25
0
50
0
7
0
0
0
0
7
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
7
7
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% R
% Ser:
7
0
7
7
7
38
13
0
0
7
7
0
13
0
0
% S
% Thr:
0
0
0
0
0
19
0
13
0
0
0
0
0
13
0
% T
% Val:
7
0
7
0
7
13
0
0
7
0
0
69
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
13
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _