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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGXT2L1
All Species:
30.61
Human Site:
Y91
Identified Species:
44.89
UniProt:
Q8TBG4
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBG4
NP_001140062.1
499
55671
Y91
L
H
D
N
I
V
E
Y
A
K
R
L
S
A
T
Chimpanzee
Pan troglodytes
XP_001137764
499
55702
Y91
L
H
D
N
I
V
E
Y
A
K
R
L
S
A
T
Rhesus Macaque
Macaca mulatta
XP_001087348
499
55544
Y91
L
H
D
N
I
V
E
Y
A
K
R
L
S
A
T
Dog
Lupus familis
XP_535690
497
55971
Y119
L
N
S
V
N
P
S
Y
Y
V
Y
I
L
W
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWU8
499
55478
F91
L
H
D
N
I
I
E
F
A
K
R
L
T
A
T
Rat
Rattus norvegicus
Q64565
512
57182
C117
V
T
V
G
V
G
H
C
H
P
K
V
T
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518449
556
61343
Y150
L
H
D
G
I
L
E
Y
A
K
R
L
S
A
T
Chicken
Gallus gallus
XP_426301
505
55954
Y95
L
H
D
N
L
V
Q
Y
A
Q
R
L
T
A
T
Frog
Xenopus laevis
Q6DEB1
509
56952
Y91
L
H
D
N
L
V
R
Y
A
E
C
L
I
S
T
Zebra Danio
Brachydanio rerio
Q7SY54
492
54717
Y92
L
H
D
S
L
V
L
Y
A
Q
R
L
Q
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU95
494
54265
C102
L
H
D
E
L
V
Q
C
A
R
T
L
T
S
K
Honey Bee
Apis mellifera
XP_392348
482
53855
C94
L
H
D
D
L
V
I
C
A
R
R
L
T
S
L
Nematode Worm
Caenorhab. elegans
P91408
467
51626
V87
G
H
C
H
P
K
V
V
E
A
I
S
K
Q
L
Sea Urchin
Strong. purpuratus
XP_001187418
531
59206
Y94
L
Y
D
Q
M
V
L
Y
A
Q
R
L
T
Q
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940M2
476
51934
N80
H
Y
Y
Q
K
P
L
N
I
V
E
G
K
M
Q
Baker's Yeast
Sacchar. cerevisiae
P07991
424
46067
H62
A
V
N
Q
G
H
C
H
P
H
I
I
K
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.1
74.5
N.A.
83.9
35.5
N.A.
68.8
72.6
71.9
66.1
N.A.
52.5
54.9
44.4
49.3
Protein Similarity:
100
99.4
97.5
81.7
N.A.
92.1
51.5
N.A.
76.4
84.5
85.2
80.9
N.A.
70.1
73.5
62.5
66.2
P-Site Identity:
100
100
100
20
N.A.
80
6.6
N.A.
86.6
73.3
60
66.6
N.A.
40
46.6
6.6
53.3
P-Site Similarity:
100
100
100
33.3
N.A.
100
40
N.A.
93.3
100
80
86.6
N.A.
73.3
80
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.6
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.9
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
0
69
7
0
0
0
57
0
% A
% Cys:
0
0
7
0
0
0
7
19
0
0
7
0
0
0
0
% C
% Asp:
0
0
69
7
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
7
0
0
32
0
7
7
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
13
7
7
0
0
0
0
0
7
0
0
0
% G
% His:
7
69
0
7
0
7
7
7
7
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
32
7
7
0
7
0
13
13
7
0
0
% I
% Lys:
0
0
0
0
7
7
0
0
0
32
7
0
19
0
7
% K
% Leu:
75
0
0
0
32
7
19
0
0
0
0
69
7
0
19
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
7
7
38
7
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
7
13
0
0
7
7
0
0
0
0
0
% P
% Gln:
0
0
0
19
0
0
13
0
0
19
0
0
7
13
7
% Q
% Arg:
0
0
0
0
0
0
7
0
0
13
57
0
0
0
0
% R
% Ser:
0
0
7
7
0
0
7
0
0
0
0
7
25
19
0
% S
% Thr:
0
7
0
0
0
0
0
0
0
0
7
0
38
0
63
% T
% Val:
7
7
7
7
7
57
7
7
0
13
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
13
7
0
0
0
0
57
7
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _