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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYNPR All Species: 22.73
Human Site: S212 Identified Species: 55.56
UniProt: Q8TBG9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBG9 NP_653243.1 265 29166 S212 S S G Q R Y L S D P M E K H S
Chimpanzee Pan troglodytes XP_516566 263 28899 S210 S S G Q R Y L S D P M E K H S
Rhesus Macaque Macaca mulatta XP_001093352 263 28885 S210 S S G Q R Y L S D P M E K H S
Dog Lupus familis XP_541820 263 28810 S210 S S G Q R Y L S D P M E K H S
Cat Felis silvestris
Mouse Mus musculus Q8BGN8 265 29210 S212 S S G Q R Y L S D P M E K H S
Rat Rattus norvegicus P22831 265 29089 S212 S S G Q R Y L S D P M E K H S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505294 149 16243 E97 G D F S S S A E F F V T V A V
Chicken Gallus gallus NP_990725 268 29395 A212 S S G Q R H A A D T M E K Q S
Frog Xenopus laevis NP_001080942 294 33049 P234 A P F M K P P P P A Q E K Q P
Zebra Danio Brachydanio rerio XP_686583 288 32098 P232 K G G A A R Y P A S S L E K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 98.4 96.5 N.A. 95.8 98.1 N.A. 43.7 83.5 53 61.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.2 99.2 97.7 N.A. 98.4 99.2 N.A. 46.7 89.5 65.3 75 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 66.6 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 6.6 80 26.6 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 10 0 20 10 10 10 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 70 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 0 80 10 0 0 % E
% Phe: 0 0 20 0 0 0 0 0 10 10 0 0 0 0 0 % F
% Gly: 10 10 80 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 60 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 10 0 0 0 0 0 0 0 80 10 0 % K
% Leu: 0 0 0 0 0 0 60 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 70 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 0 10 10 20 10 60 0 0 0 0 10 % P
% Gln: 0 0 0 70 0 0 0 0 0 0 10 0 0 20 10 % Q
% Arg: 0 0 0 0 70 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 70 70 0 10 10 10 0 60 0 10 10 0 0 0 70 % S
% Thr: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 60 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _