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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LPPR1 All Species: 25.45
Human Site: S248 Identified Species: 50.91
UniProt: Q8TBJ4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBJ4 NP_060223.2 325 35795 S248 L T G L N R V S E Y R N H C S
Chimpanzee Pan troglodytes XP_001135580 309 34087 D240 E Y R N H C S D V I A G F I L
Rhesus Macaque Macaca mulatta XP_001111433 325 35779 S248 L T G L N R V S E Y R N H C S
Dog Lupus familis XP_538755 325 35838 S248 L T G L N R V S E Y R N H C S
Cat Felis silvestris
Mouse Mus musculus Q8BFZ2 325 35913 S248 L T G L N R V S E Y R N H C S
Rat Rattus norvegicus Q6WAY2 325 35868 S248 L T G L N R V S E Y R N H C S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511381 419 44877 A255 L V G V V R V A E Y R N H W S
Chicken Gallus gallus XP_424888 309 34095 D240 E Y R N H C S D V I A G F I L
Frog Xenopus laevis Q6GM05 314 34960 A241 L T G I N R V A E Y R N H W S
Zebra Danio Brachydanio rerio Q6IQH6 333 36474 S247 L T G L N R V S E Y R N H C S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10022 341 39009 T246 G I S F S R I T D N K H H W S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZU49 327 36665 W244 I S R V D D Y W H H W Q D V F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.4 99.3 98.4 N.A. 96.3 96 N.A. 41.5 88 55 77.4 N.A. N.A. N.A. 24.3 N.A.
Protein Similarity: 100 95 99.6 99.3 N.A. 98.4 98.1 N.A. 54.4 92.6 73.2 86.7 N.A. N.A. N.A. 43.4 N.A.
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 66.6 0 80 100 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 80 6.6 93.3 100 N.A. N.A. N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 17 0 0 17 0 0 0 0 % A
% Cys: 0 0 0 0 0 17 0 0 0 0 0 0 0 50 0 % C
% Asp: 0 0 0 0 9 9 0 17 9 0 0 0 9 0 0 % D
% Glu: 17 0 0 0 0 0 0 0 67 0 0 0 0 0 0 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 0 0 17 0 9 % F
% Gly: 9 0 67 0 0 0 0 0 0 0 0 17 0 0 0 % G
% His: 0 0 0 0 17 0 0 0 9 9 0 9 75 0 0 % H
% Ile: 9 9 0 9 0 0 9 0 0 17 0 0 0 17 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % K
% Leu: 67 0 0 50 0 0 0 0 0 0 0 0 0 0 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 17 59 0 0 0 0 9 0 67 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Q
% Arg: 0 0 25 0 0 75 0 0 0 0 67 0 0 0 0 % R
% Ser: 0 9 9 0 9 0 17 50 0 0 0 0 0 0 75 % S
% Thr: 0 59 0 0 0 0 0 9 0 0 0 0 0 0 0 % T
% Val: 0 9 0 17 9 0 67 0 17 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 9 0 0 25 0 % W
% Tyr: 0 17 0 0 0 0 9 0 0 67 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _