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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LPPR1 All Species: 25.76
Human Site: T218 Identified Species: 51.52
UniProt: Q8TBJ4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBJ4 NP_060223.2 325 35795 T218 A T M Y I T S T I K T K S S R
Chimpanzee Pan troglodytes XP_001135580 309 34087 L210 I K T K S S R L A K P V L C L
Rhesus Macaque Macaca mulatta XP_001111433 325 35779 T218 A T M Y I T S T I K T K S S R
Dog Lupus familis XP_538755 325 35838 T218 A T M Y I T S T I K T K S S R
Cat Felis silvestris
Mouse Mus musculus Q8BFZ2 325 35913 T218 A T M Y I T S T I K T K S S R
Rat Rattus norvegicus Q6WAY2 325 35868 T218 A T M Y I T S T I K T K S S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511381 419 44877 V225 T V M Y V T L V F K L K G S R
Chicken Gallus gallus XP_424888 309 34095 L210 I K T K S S R L A K P V L C L
Frog Xenopus laevis Q6GM05 314 34960 T211 L A M Y I T S T I K A K G T R
Zebra Danio Brachydanio rerio Q6IQH6 333 36474 T217 V T M Y I T S T I K T K S S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10022 341 39009 L216 A L Y I Q A R L G P V L N N R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZU49 327 36665 N214 S G K I K A F N N E G H V A K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.4 99.3 98.4 N.A. 96.3 96 N.A. 41.5 88 55 77.4 N.A. N.A. N.A. 24.3 N.A.
Protein Similarity: 100 95 99.6 99.3 N.A. 98.4 98.1 N.A. 54.4 92.6 73.2 86.7 N.A. N.A. N.A. 43.4 N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 46.6 6.6 66.6 93.3 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. 53.3 13.3 73.3 93.3 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 9 0 0 0 17 0 0 17 0 9 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 9 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 0 0 0 9 0 9 0 17 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 17 0 0 17 59 0 0 0 59 0 0 0 0 0 0 % I
% Lys: 0 17 9 17 9 0 0 0 0 84 0 67 0 0 9 % K
% Leu: 9 9 0 0 0 0 9 25 0 0 9 9 17 0 17 % L
% Met: 0 0 67 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 9 0 0 0 9 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 9 17 0 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 25 0 0 0 0 0 0 0 75 % R
% Ser: 9 0 0 0 17 17 59 0 0 0 0 0 50 59 0 % S
% Thr: 9 50 17 0 0 67 0 59 0 0 50 0 0 9 0 % T
% Val: 9 9 0 0 9 0 0 9 0 0 9 17 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 67 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _