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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SETD6 All Species: 13.64
Human Site: T328 Identified Species: 30
UniProt: Q8TBK2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBK2 NP_001153777 473 53020 T328 A A L Q G T K T E A E R H L V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001102146 481 54024 T329 A A L Q G T K T E A E R L L A
Dog Lupus familis XP_544379 453 51445 V308 A A L Q G T K V E A E R L L L
Cat Felis silvestris
Mouse Mus musculus Q9CWY3 473 52942 D328 A A L Q G T K D E T E K L L V
Rat Rattus norvegicus NP_001099637 474 53343 D329 A A L Q G T E D E T E R L L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507526 513 58286 T368 A A L Q G A E T E A E R Q S V
Chicken Gallus gallus Q5ZK17 447 50631 N301 A A L Q R A K N E A Q Q Q L V
Frog Xenopus laevis Q6INM2 455 52340 T308 A A L Q A A Q T E D D R L E M
Zebra Danio Brachydanio rerio Q803K4 460 52989 S307 A A A Q V A R S E A N Q Q L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181160 466 53174 F323 E A R T H E A F S A T M D E R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12504 494 57270 N307 L K E T F E T N T E F L D R C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 94.8 83.9 N.A. 77.1 77.6 N.A. 61.4 64.4 56.2 49 N.A. N.A. N.A. N.A. 40.8
Protein Similarity: 100 N.A. 95.8 86.8 N.A. 83.3 82.9 N.A. 71.1 76.1 71.2 67.8 N.A. N.A. N.A. N.A. 57.7
P-Site Identity: 100 N.A. 86.6 80 N.A. 73.3 66.6 N.A. 73.3 60 46.6 40 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 N.A. 86.6 86.6 N.A. 80 80 N.A. 80 73.3 66.6 66.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 82 91 10 0 10 37 10 0 0 64 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 0 0 0 19 0 10 10 0 19 0 0 % D
% Glu: 10 0 10 0 0 19 19 0 82 10 55 0 0 19 0 % E
% Phe: 0 0 0 0 10 0 0 10 0 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 55 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 46 0 0 0 0 10 0 0 0 % K
% Leu: 10 0 73 0 0 0 0 0 0 0 0 10 46 64 28 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 19 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 82 0 0 10 0 0 0 10 19 28 0 0 % Q
% Arg: 0 0 10 0 10 0 10 0 0 0 0 55 0 10 10 % R
% Ser: 0 0 0 0 0 0 0 10 10 0 0 0 0 10 0 % S
% Thr: 0 0 0 19 0 46 10 37 10 19 10 0 0 0 0 % T
% Val: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 37 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _