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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD6
All Species:
30.61
Human Site:
T363
Identified Species:
67.33
UniProt:
Q8TBK2
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBK2
NP_001153777
473
53020
T363
I
G
R
E
E
V
L
T
E
E
E
L
T
T
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102146
481
54024
T364
I
G
R
E
E
V
L
T
E
E
E
L
I
T
T
Dog
Lupus familis
XP_544379
453
51445
T343
I
G
R
E
E
V
L
T
E
E
E
L
T
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWY3
473
52942
T363
I
G
C
E
E
V
L
T
E
E
E
L
A
T
T
Rat
Rattus norvegicus
NP_001099637
474
53343
T364
I
G
R
E
E
V
L
T
E
E
E
L
A
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507526
513
58286
T403
I
G
W
E
E
V
L
T
E
E
E
L
S
A
T
Chicken
Gallus gallus
Q5ZK17
447
50631
T336
L
G
W
D
E
V
L
T
E
E
E
L
S
V
T
Frog
Xenopus laevis
Q6INM2
455
52340
T343
F
G
L
E
E
V
M
T
E
E
E
L
K
V
S
Zebra Danio
Brachydanio rerio
Q803K4
460
52989
T342
F
G
Q
S
G
S
L
T
Y
H
E
L
Y
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181160
466
53174
A355
I
G
M
D
G
V
L
A
E
D
E
V
F
M
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12504
494
57270
L353
L
L
P
Q
L
I
L
L
V
Q
I
L
T
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.8
83.9
N.A.
77.1
77.6
N.A.
61.4
64.4
56.2
49
N.A.
N.A.
N.A.
N.A.
40.8
Protein Similarity:
100
N.A.
95.8
86.8
N.A.
83.3
82.9
N.A.
71.1
76.1
71.2
67.8
N.A.
N.A.
N.A.
N.A.
57.7
P-Site Identity:
100
N.A.
93.3
100
N.A.
86.6
93.3
N.A.
80
66.6
60
46.6
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
N.A.
93.3
100
N.A.
86.6
93.3
N.A.
86.6
86.6
73.3
53.3
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
19
10
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
64
73
0
0
0
82
73
91
0
0
0
0
% E
% Phe:
19
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
91
0
0
19
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
64
0
0
0
0
10
0
0
0
0
10
0
10
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
19
10
10
0
10
0
91
10
0
0
0
91
0
0
10
% L
% Met:
0
0
10
0
0
0
10
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
10
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
37
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
10
0
0
0
0
0
0
19
0
10
% S
% Thr:
0
0
0
0
0
0
0
82
0
0
0
0
28
55
73
% T
% Val:
0
0
0
0
0
82
0
0
10
0
0
10
0
19
0
% V
% Trp:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _